5-(4-Nitrophenyl)-N-(p-tolyl)-1,3,4-thiadiazol-2-amine CAS 827580-69-8
| CAS No. | 827580-69-8 |
| Molecular Formula | C15H12N4O2S |
| Molecular Weight | 312.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-(4-Nitrophenyl)-N-(p-tolyl)-1,3,4-thiadiazol-2-amine (CAS 827580-69-8) is a high-purity analytical reference standard with the molecular formula C15H12N4O2S and a molecular weight of 312.35 g/mol.
The molecular framework of 5-(4-Nitrophenyl)-N-(p-tolyl)-1,3,4-thiadiazol-2-amine (C15H12N4O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12N4O2S |
| Molecular Weight | 312.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Nitrophenyl Standards
- 3-(4-Nitrophenyl)-6-phenyl-3,4-dihydro-1,3,5-triazine-2(1H)-thione (CAS 315707-47-2)
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Recommended Standards
- 5-(Phenylsulfonyl)-2-(pyridin-2-yl)pyrimidin-4-amine (CAS 339107-42-5)
- 3,5-Difluoro-5-(5,5-dimethyl-1,3-dioxan-2-yl)valerophenone (CAS 898787-05-8)
- 5-(Phenylsulfonyl)-2-(pyridin-3-yl)pyrimidin-4-amine (CAS 339107-51-6)
- 3,4-Difluoro-N-((1-(2-methoxyethyl)piperidin-4-yl)methyl)benzamide (CAS 954077-62-4)
- ((4AR,8aS)-1-(4-fluorophenyl)-6-((2-methyl-2H-1,2,3-triazol-4-yl)sulfonyl)-1,4,5,6,7,8,8a,9-octahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone (CAS 1781244-77-6)
- 1-cyclopropylethane-1,2-diol (CAS 134511-23-2)
- Purpureaglycoside B CRS (CAS 19855-39-1)
- 12-Methyltridecancarbonsaeure 12-Methyltridecansaeure 12-methyltridecanoic acid 12-methyltridecylic acid 2724-57-4 C14:0 iso CHEBI:43722 aseanostatin P1 i14:0 iso-14:0 iso-C14:0 isomyristic acid (CAS 2724-57-4)
- 3-(2-Methoxybenzyl)-2-thioxo-2,3-dihydrothieno-[3,2-d]pyrimidin-4(1H)-one (CAS 1155033-89-8)
- 1-(5-(4-Methoxyphenyl)-1-tosyl-1H-pyrrol-2-yl)ethan-1-one (CAS 827024-10-2)
- Methyl-5-hydroxy-3-p-tolyl-6,7,8,9-tetrahydro-5H- benzo[7]annulene-6-carboxylate (CAS 350022-61-6)
- 2-((Diethylamino)methyl)benzenethiol (CAS 1203644-33-0)
- tert-butyl N-[(1S)-1-methylbut-3-ynyl]carbamate (CAS 1312714-92-3)
- Semaglutide impurity 194 (CAS CATO-C4X-2226194)
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