5-(2-Chloro-phenyl)-[1,3,4]thiadiazol-2-ylamine CAS 828-81-9
| CAS No. | 828-81-9 |
| Molecular Formula | C8H6ClN3S |
| Molecular Weight | 211.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(2-Chloro-phenyl)-[1,3,4]thiadiazol-2-ylamine.
CATO supplies 5-(2-Chloro-phenyl)-[1,3,4]thiadiazol-2-ylamine (CAS 828-81-9), a certified reference material (molecular formula C8H6ClN3S, MW 211.67 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, 5-(2-Chloro-phenyl)-[1,3,4]thiadiazol-2-ylamine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 211.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(2-Chloro-phenyl)-[1,3,4]thiadiazol-2-ylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClN3S |
| Molecular Weight | 211.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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- 4-Chloro-7-methoxy-6-(methylthio)pyrido[3,2-d]pyrimidine (CAS 1263363-54-7)
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- 2-Chloro-4-(thiazol-5-yl)phenol (CAS 1823423-09-1)
- 2-Chloro-N-(tetrahydro-1,1-dioxido-3-thienyl)acetamide (CAS 5612-41-9)
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Recommended Standards
- 5-(2-Chlorophenyl)-1,2,4-thiadiazol-3-amine (CAS 42053-84-9)
- 4-(6-Chloropyridin-3-yl)thiazol-2-amine (CAS 885279-42-5)
- 5-(2-Chlorophenyl)-1H-1,2,4-triazole-3-thiol (CAS 58755-00-3)
- 4-(5-Chlorothiophen-2-yl)pyrimidin-2(1H)-imine (CAS 855308-65-5)
- 1-(2-(Trifluoromethoxy)phenyl)piperazine (CAS 186386-95-8)
- n-(2-Aminophenyl)pyrrolidine-1-carboxamide (CAS 1118786-84-7)
- 2-Toluene glycidyl ether (CAS 2210-79-9)
- 1,2,4,5-tetrazine-3,6-dicarboxylic acid;disodium salt (CAS 113631-48-4)
- 3-[(2,5-Difluorophenyl)methoxy]cyclobutan-1-amine Hydrochloride, cis (CAS 1807940-88-0)
- 3-(5-Amino-1,3,4-oxadiazol-2-yl)benzonitrile (CAS 1016521-87-1)
- Moxifloxacin Impurity 46 (CAS 141290-02-0)
- 4-(2,4-Dihydroxypyrimidin-5-yl)thiophene-2-carbaldehyde (CAS 1261923-05-0)
- Ethyl 2-(6,8-dichloroimidazo[1,2-a]pyridin-2-yl)acetate (CAS 59128-03-9)
- Semaglutide impurity 29 (CAS 110990-08-4)
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