3-Hydroxybutanoic (2S)-4-(tosyloxy)pyrrolidine-2-carboxylic anhydride CAS 828276-86-4
| CAS No. | 828276-86-4 |
| Molecular Formula | C14H20O6S |
| Molecular Weight | 316.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Hydroxybutanoic (2S)-4-(tosyloxy)pyrrolidine-2-carboxylic anhydride (CAS 828276-86-4), molecular formula C14H20O6S and molecular weight 316.37 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Hydroxybutanoic (2S)-4-(tosyloxy)pyrrolidine-2-carboxylic anhydride (C14H20O6S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H20O6S |
| Molecular Weight | 316.37 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Sulfur Atoms | 1 |
Related Hydroxybutanoic Standards
- 3-Hydroxybutanoic (2S)-4-((phenylsulfonyl)oxy)pyrrolidine-2-carboxylic anhydride (CAS 828276-78-4)
- 3-Hydroxybutanoic (2S)-4-iodo-1-methylpyrrolidine-2-carboxylic anhydride (CAS 828276-68-2)
- 3-Hydroxybutanoic (2S)-4-iodo-2-methylpyrrolidine-2-carboxylic anhydride (CAS 828276-67-1)
- 3-Hydroxybutanoic (2S)-4-iodopyrrolidine-2-carboxylic anhydride (CAS 828276-64-8)
- 2-Ethyl-3-hydroxybutanoic acid (CAS 854851-58-4)
- (S)-3-Hydroxybutanoic acid (sodium) (CAS 127604-16-4)
- (R)-2-Hydroxybutanoic acid (CAS 20016-85-7)
- (S)-2-Hydroxybutanoic acid (CAS 3347-90-8)
Recommended Standards
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- Irinotecan Impurity 9 (CAS 80758-83-4)
- 2,2'-[[3-(Dioctadecylamino)propyl]imino]bisethanol 35607-20-6 Avridine CP 20961 CP-20961 N,N-Dioctadecyl-N inverted exclamation marka,N inverted exclamation marka-bis(2-hydroxyethyl)-1,3-diaminopropane N,N-Dioctadecyl-N inverted exclamation marka,N inverted exclamation marka-bis(2-hydroxyethyl)propanediamine N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)-1,3-diaminopropane N,N-Dioctadecyl-N',N'-bis(2-hydroxyethyl)propanediamine (CAS 35607-20-6)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
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