Ethyl 2-((4-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)thio)acetate CAS 828277-81-2
| CAS No. | 828277-81-2 |
| Molecular Formula | C15H14F2N2O3S |
| Molecular Weight | 340.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 340.35 g/mol gives Ethyl 2-((4-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)thio)acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2-((4-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)thio)acetate (CAS 828277-81-2), molecular formula C15H14F2N2O3S and molecular weight 340.35 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 2-((4-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)thio)acetate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 340.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 2-((4-(4-(difluoromethoxy)phenyl)pyrimidin-2-yl)thio)acetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H14F2N2O3S |
| Molecular Weight | 340.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 2-((4-(Difluoromethoxy)phenyl)sulfonyl)isoindolin-5-amine (CAS 2098081-86-6)
- Ethyl 2-((4-(3-(difluoromethoxy)phenyl)pyrimidin-2-yl)thio)acetate (CAS 832147-32-7)
- Propyl 4-(2-(difluoromethoxy)phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 121112-76-3)
- 4-[4-(difluoromethoxy)phenyl]-5-(piperidin-1-ylmethyl)-4H-1,2,4-triazole-3-thiol (CAS 790270-93-8)
- 6-(Difluoromethoxy)-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid (CAS 121935-03-3)
- 2-(Difluoromethoxy)-5-iodo-3-(trifluoromethyl)pyridine (CAS 1803729-60-3)
- Ethyl 2-(difluoromethoxy)-5-iodobenzoate (CAS 1131587-26-2)
- Ethyl 4-(difluoromethoxy)-3-iodobenzoate (CAS 1131614-53-3)
Recommended Standards
- Ethyl 4-(4-fluorophenyl)-6-hydroxy-2-phenyl-4,5-dihydro-5-pyrimidinecarboxylate (CAS 477867-27-9)
- Ethyl (Z)-2-((2,6-difluorobenzoyl)imino)-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylate (CAS 476643-66-0)
- Methyl 2-{[(1E)-2-{[(ethoxycarbonyl)amino]carbonyl}-3-oxobut-1-en-1-yl]amino}thiophene-3-carboxylate (CAS 338750-48-4)
- 6-(3,4-Dimethoxyphenyl)-2-(3-fluorobenzyl)pyridazin-3(2H)-one (CAS 899946-56-6)
- 4-chloro-2-cyclopropyl-pyrimidine (CAS 1044771-74-5)
- Ethyl 2,2-difluorocyclopropanecarboxylate (CAS 151324-64-0)
- 1,2-Ethanediol Disodium Salt (CAS 10604-71-4)
- Hyperforin acetate (CAS 68324-06-1)
- Furan-2-ylmethyl 4-nitrobenzoate (CAS 4449-29-0)
- N-Phenylthiophen-2-amine (CAS 940-32-9)
- (5-(Trifluoromethyl)isoxazol-3-yl)methanamine (CAS 1364678-08-9)
- 5-(Cyclohexylmethyl)-2-(methylthio)phenol (CAS 1243283-37-5)
- Potassium 5-(isothiazol-5-yl)-1,3,4-oxadiazole-2-carboxylate (CAS 2137785-72-7)
- Peptide Impurity 82 (CAS 10491-78-8)
Why CATO?
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