(E)-4-((3-((4-Chlorophenoxy)methyl)-4-methoxybenzylidene)amino)-5-(trifluoromethyl)-4H-1,2,4-triazole-3-thiol CAS 828286-00-6
| CAS No. | 828286-00-6 |
| Molecular Formula | C18H14ClF3N4O2S |
| Molecular Weight | 442.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-4-((3-((4-Chlorophenoxy)methyl)-4-methoxybenzylidene)amino)-5-(trifluoromethyl)-4H-1,2,4-triazole-3-thiol (CAS 828286-00-6), molecular formula C18H14ClF3N4O2S and molecular weight 442.84 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (E)-4-((3-((4-Chlorophenoxy)methyl)-4-methoxybenzylidene)amino)-5-(trifluoromethyl)-4H-1,2,4-triazole-3-thiol (C18H14ClF3N4O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 442.84 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (E)-4-((3-((4-Chlorophenoxy)methyl)-4-methoxybenzylidene)amino)-5-(trifluoromethyl)-4H-1,2,4-triazole-3-thiol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14ClF3N4O2S |
| Molecular Weight | 442.84 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related E Standards
- (2Z)-7-(4-Chlorophenoxy)-2-[(3-methylthiophen-2-yl)methylidene]-3-phenyl-2,3-dihydro-1H-inden-1-one (CAS 337921-32-1)
- 2-((5-((4-Chlorophenoxy)methyl)-4-ethyl-4H-1,2,4-triazol-3-yl)thio)-1-(3,4-dihydroquinolin-1(2H)-yl)ethan-1-one (CAS 483285-92-3)
- N-(4-(4-Chlorophenoxy)phenyl)-1-(3,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 890887-23-7)
- 3-{1-[2-(4-chlorophenoxy)acetyl]piperidin-4-yl}-4-[(4-fluorophenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775524-46-3)
- (5-(4-Chlorophenoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl 4-chlorobenzoate (CAS 955964-18-8)
- 4-(4-Chlorophenoxy)-6-(((4-chlorophenyl)thio)methyl)-2-(pyridin-3-yl)pyrimidine (CAS 860609-59-2)
- 4-(4-Chlorophenoxy)-6-(((4-chlorophenyl)thio)methyl)-2-phenylpyrimidine (CAS 303147-12-8)
- (2Z)-7-(4-Chlorophenoxy)-2-[(4-methylphenyl)methylidene]-3-phenyl-2,3-dihydro-1H-inden-1-one (CAS 337921-25-2)
Recommended Standards
- (E)-{1-[3-(morpholin-4-yl)-5-(trifluoromethyl)pyridin-2-yl]ethylidene}amino N-(4-chlorophenyl)carbamate 866145-20-2 9T-0823 (CAS 866145-20-2)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(4-methoxyphenyl)-1-methyl-1H-imidazole-5-carboxamide (CAS 339278-15-8)
- N-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-oxoethoxy)benzamide (CAS 303150-03-0)
- 2-((4-Allyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-chloro-3-(trifluoromethyl)phenyl)acetamide (CAS 577770-76-4)
- 5-Amino-1-(5-bromo-2-chlorophenyl)-3-methyl-1H-pyrazole-4-carbonitrile (CAS 2197061-81-5)
- Tert-butyl 4-((5-chloropyrimidin-2-yl)(methyl)amino)piperidine-1-carboxylate (CAS 1261231-31-5)
- N4-Cyclohexylpyrimidine-4,5-diamine (CAS 1044767-86-3)
- N-(4-chlorophenyl)-2-(3-(thiophen-2-yl)-4,5-dihydroisoxazole-5-carbonyl)hydrazine-1-carboxamide (CAS 478259-23-3)
- Ethyl 4-(benzofuran-2-yl)-2,4-dioxobutanoate (CAS 106276-58-8)
- 1-(Pyrazin-2-yl)piperidin-4-amine (CAS 440102-39-6)
- Troxipide Impurity 28 (CAS CATO-C4X-214828)
- 2-(1-(Tert-butyl)-1H-pyrazole-4-carbonyl)phenyl furan-2-carboxylate (CAS 955961-65-6)
- (3,4-Difluorophenyl)(phenyl)methanol (CAS 182192-93-4)
- Semaglutide Impurity 9 (CAS CATO-C4X-22269)
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