4-[(4-Chloro-1-naphthyl)oxy]-3-(trifluoromethyl)-phenylamine CAS 83054-44-8
| CAS No. | 83054-44-8 |
| Molecular Formula | C17H11ClF3NO |
| Molecular Weight | 337.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-[(4-Chloro-1-naphthyl)oxy]-3-(trifluoromethyl)-phenylamine (C17H11ClF3NO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
4-[(4-Chloro-1-naphthyl)oxy]-3-(trifluoromethyl)-phenylamine (CAS 83054-44-8), molecular formula C17H11ClF3NO and molecular weight 337.72 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-[(4-Chloro-1-naphthyl)oxy]-3-(trifluoromethyl)-phenylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H11ClF3NO |
| Molecular Weight | 337.72 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- N-(4-Chloro-2-trifluoroacetyl-6-methoxyphenyl)-2,2-dimethylpropanamide (CAS 1076199-86-4)
- 2-[(4-Chloro-1-naphthyl)oxy]-5-(trifluoromethyl)-phenylamine (CAS 946682-78-6)
- 4-[(4-Chloro-1-naphthyl)oxy]-2-(trifluoromethyl)-phenylamine (CAS 946663-34-9)
- N-(3-chloro-4-methoxybenzyl)-2,4-dinitroaniline (CAS 478259-76-6)
- 3-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanoic acid (CAS 1227954-73-5)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N1,N1,N3,N3-tetramethylmalonamide (CAS 338406-79-4)
- 2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetohydrazide (CAS 338979-10-5)
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Recommended Standards
- Dimethyl 1-(2-(4-chlorophenyl)-2-oxoethyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 1350929-63-3)
- tert-Butyl 4-chloro-2-(trifluoromethyl)-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate (CAS 1274804-46-4)
- 1-(3-Chlorophenyl)-4-(3-(trifluoromethyl)phenyl)-1H-pyrazol-5-amine (CAS 324008-97-1)
- 4-[(2,2,2-trifluoroethyl)sulfamoyl]benzene-1-sulfonyl chloride (CAS 1036475-80-5)
- 2-((5-(4-Chlorophenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-ethylphenyl)acetamide (CAS 482654-85-3)
- 5-(3-Pyridinyl)-1,2,4-oxadiazol-3-amine (CAS 73631-18-2)
- 2-Methyl-7-(pyridin-3-yl)-1H-indole (CAS 919119-77-0)
- Methyl N-methyl-5-nitro-2-pyrrolecarboxylate (CAS 13138-75-5)
- 3-(2,6-Dimethylbenzoyl)phenyl acetate (CAS 890099-14-6)
- Tert-butyl 4-(((4-fluorophenyl)sulfinyl)methyl)piperidine-1-carboxylate (CAS 1353989-67-9)
- Ethyl 3,3,3-trifluoro-2-(4-fluorophenyl)-2-hydroxypropanoate (CAS 552314-23-5)
- {3-Oxabicyclo[3.1.0]hexan-1-yl}methanamine (CAS 1203707-10-1)
- 4-Bromo-5-((methylthio)methyl)isoxazol-3(2H)-one (CAS 89661-19-8)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
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