Ethyl 3-chloro-5-fluoro-4-hydroxybenzoate CAS 832087-79-3
| CAS No. | 832087-79-3 |
| Molecular Formula | C9H8ClFO3 |
| Molecular Weight | 218.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 3-chloro-5-fluoro-4-hydroxybenzoate (CAS 832087-79-3) is a high-purity analytical reference standard with the molecular formula C9H8ClFO3 and a molecular weight of 218.61 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Ethyl 3-chloro-5-fluoro-4-hydroxybenzoate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 218.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8ClFO3 |
| Molecular Weight | 218.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
Related Ethyl Standards
- 2-(3-Chloro-5-fluoro-4-methoxyphenyl)acetic acid (CAS 1000544-65-9)
- 2-(2-Chloro-6-fluoro-3-methoxyphenyl)acetic acid (CAS 1017777-68-2)
- 6-Chloro-2-fluoro-3-methoxyphenylacetic acid (CAS 1017777-83-1)
- 3-Chloro-4-ethoxy-5-fluorobenzoic acid (CAS 1017778-72-1)
- 3-(2-Chloro-6-fluorophenyl)-2-hydroxypropanoic acid (CAS 1181561-52-3)
- Methyl 2-(4-chloro-3-fluorophenyl)-2-hydroxyacetate (CAS 1248821-36-4)
- 3-(2-Chloro-6-fluorophenyl)-3-hydroxypropanoic acid (CAS 1249515-00-1)
- 5-Chloro-2-fluoro-N-methoxy-N-methyl-3-pyridinecarboxamide (CAS 1256834-71-5)
Recommended Standards
- Ethyl 2-amino-6-chloro-5-fluoronicotinate (CAS 2131059-69-1)
- Ethyl 4-amino-6-chloro-5-fluoronicotinate (CAS 2454397-74-9)
- 6-Fluoro-2-Chloro-3-(methoxymethoxy)benzaldehyde (CAS 2179038-43-6)
- Methyl 2-chloro-4-fluoro-3-methoxybenzoate (CAS 2386559-04-0)
- 3-Bromo-9-vinyl-9H-carbazole (CAS 46499-01-8)
- Barium 2-amino-3-(phosphonooxy)propanoate(1:x) (CAS 58823-92-0)
- 3,3,3-Trifluoro-2-(3-fluorophenyl)-2-hydroxypropanoic acid (CAS 1544848-23-8)
- 3-Chloro-4-fluorobenzo[b]thiophene-2-carbohydrazide (CAS 774586-50-4)
- (6-(1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)pyridin-3-yl)boronic acid (CAS 928160-90-1)
- 2-Chloro-5-methyl-1,3,4-oxadiazole (CAS 98321-75-6)
- 1-(4-(4-Amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl)phenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea (CAS 501693-25-0)
- 3-Formyl-5-(trifluoromethyl)benzenesulfonyl chloride (CAS 1393534-47-8)
- 4-(1,3-Dioxaindan-5-yl)-3-ethyl-1h-pyrazol-5-amine (CAS 1187767-30-1)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
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