5-Methoxy-2-methylpyrimidine-4-thiol CAS 83256-74-0

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies 5-Methoxy-2-methylpyrimidine-4-thiol (CAS 83256-74-0), a certified reference material (molecular formula C6H8N2OS, MW 156.21 g/mol) for analytical method development and quality control.

The molecular framework of 5-Methoxy-2-methylpyrimidine-4-thiol (C6H8N2OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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