3-Bromo-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 832740-70-2
| CAS No. | 832740-70-2 |
| Molecular Formula | C9H5BrF3N3O2 |
| Molecular Weight | 324.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Bromo-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (C9H5BrF3N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 3-Bromo-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 832740-70-2), a certified reference material (molecular formula C9H5BrF3N3O2, MW 324.05 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Bromo-5-methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H5BrF3N3O2 |
| Molecular Weight | 324.05 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- Methyl 6-bromo-2-(trifluoromethyl)imidazo[1,5-a]pyrimidine-8-carboxylate (CAS 2138253-50-4)
- 7-Bromo-5-(pentafluoro-λ6-sulfanyl)benzo[d]oxazole (CAS 1432075-78-9)
- 1-(5-Bromo-2-(trifluoromethyl)pyridin-4-yl)-2,2,2-trifluoroethanol (CAS 1375303-18-6)
- 2-Bromo-6-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)pyridine (CAS 1707391-21-6)
- 5-Bromo-2-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)pyridine (CAS 1713160-07-6)
- 3-Bromo-2-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)pyridine (CAS 1774894-72-2)
- 3-Bromo-5-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)pyridine (CAS 1774894-82-4)
- 4-Bromo-3-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)pyridine (CAS 1774895-33-8)
Recommended Standards
- S-(2,6-Dibromobenzyl) ethanethioate (CAS 256651-54-4)
- 1-Hydroxy-1,3-dioxo-1,3-dihydro-1λ5-benzo[d][1,2]iodaoxole-4-carboxylic acid (CAS 426832-99-7)
- N-(2-furylmethyl)methanesulfonamide (CAS 6341-33-9)
- 4-(Chloromethyl)-3-(difluoromethyl)-5-(trifluoromethoxy)picolinoyl chloride (CAS 1805183-05-4)
- 1-(3-(Diethylamino)propyl)guanidine (CAS 45017-94-5)
- 2-(4-Bromophenyl)-1-cyclobutylethan-1-one (CAS 1183705-75-0)
- 1-(5-Fluoro-1-benzofuran-2-yl)ethan-1-amine (CAS 159009-23-1)
- Oseltamivir Impurity 68 (CAS CATO-C4X-172068)
- Isosorbide Dinitrate (CAS 87-33-2)
- (4S,4′S)-2,2′-(1-Methylethylidene)bis[4,5-dihydro-4-(4-methylphenyl)oxazole] (CAS 923571-59-9)
- S-((trans-1-(Cyanomethyl)-2-fluorocyclopropyl)methyl) ethanethioate (CAS 1624262-24-3)
- 5-(Trifluoromethoxy)pyridin-3-amine hydrochloride (CAS 2841453-88-9)
- Sodium 2-hydroxy-2-(4-hydroxyphenyl)acetate (CAS 69322-01-6)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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