Benzhexol Impurity 10 CAS 833-86-3
| CAS No. | 833-86-3 |
| Molecular Formula | C13H17NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Benzhexol Impurity 10.
As a process- or degradation-related impurity, Benzhexol Impurity 10 (CAS 833-86-3, C13H17NOHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Benzhexol Impurity 10 (C13H17NOHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 239.74 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Benzhexol Impurity 10 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H17NO HCl |
| Molecular Weight | 239.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Benzhexol Standards
- Benzhexol Impurity 3 (CAS 1071664-63-5)
- Benzhexol Impurity 9 (CAS 1193-81-3)
- Benzhexol Impurity 4 (CAS 127865-20-7)
- Benzhexol Impurity 01 (CAS 13150-57-7)
- Benzhexol Impurity 11 (CAS 161564-79-0)
- Benzhexol Impurity 20 (CAS 29334-16-5)
- Benzhexol Impurity 15（Proadifen） (CAS 302-33-0)
- Benzhexol Impurity 02 HCl (CAS 30778-27-9)
Recommended Standards
- Rasagiline Impurity 35 (CAS CATO-C4X-191335)
- Belumosudil Impurity 62 (CAS CATO-C4X-298862)
- Minoxidil Impurity 42 (CAS 3337-17-5)
- Tert-butyl 3-(3-methoxy-3-oxopropyl)-1H-indole-1-carboxylate (CAS 253605-13-9)
- 2-Methyl-2H-pyrazolo[4,3-d]pyrimidin-7-amine (CAS 1394023-53-0)
- 4-Nitrosodiphenylamine (CAS 156-10-5)
- 5-Bromo-3-(2,2-difluoroethyl)-6-methylpyrimidin-4(3h)-one (CAS 1520677-44-4)
- 1-[3-(1H-imidazol-1-yl)propyl]-5-methyl-1H-benzimidazol-2-amine (CAS 1155597-09-3)
- Tris(4-chlorophenyl)methane (CAS 27575-78-6)
- Galanin-Like Peptide (porcine) trifluoroacetate salt (CAS 245114-96-9)
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