4-Chloro-5-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine CAS 833481-37-1
| CAS No. | 833481-37-1 |
| Molecular Formula | C7H5ClIN3 |
| Molecular Weight | 293.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-5-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 833481-37-1) is a high-purity analytical reference standard with the molecular formula C7H5ClIN3 and a molecular weight of 293.49 g/mol.
The molecular framework of 4-Chloro-5-iodo-7-methyl-7H-pyrrolo[2,3-d]pyrimidine (C7H5ClIN3) is characterized by a nitrile group, chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5ClIN3 |
| Molecular Weight | 293.49 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 6-chloro-3-iodo-1H-indazol-5-amine (CAS 1000342-50-6)
- 4-Chloro-3-iodo-1H-indazol-7-amine (CAS 1000343-04-3)
- 5-chloro-4-iodo-2-methoxybenzonitrile (CAS 1057339-09-9)
- 4-Chloro-5-iodo-2-methyl-7H-pyrrolo[2,3-d]pyrimidine, 97% (CAS 1060815-92-0)
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- 2-Chloro-7-iodo-5-methyl-5H-pyrrolo[3,2-d]pyrimidine, 97% (CAS 1152475-62-1)
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Recommended Standards
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- 3-Methyl-5-pentadecylisoxazole (CAS 649721-01-7)
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- 1-(6-(Ethoxycarbonyl)-5,6,7,8-tetrahydropyrido[4,3-c]pyridazin-3-yl)-1H-imidazole-4-carboxylic acid (CAS 1713463-23-0)
- Trelagliptin Impurity 54 (CAS 1261686-95-6)
- 4-Carbamoyl-1-methyl-1h-pyrazole-3-carboxylic acid (CAS 1006458-39-4)
- 1-(Cyclohexylmethyl)-1H-indole-3-carboxylic Acid Methyl Ester (CAS 858515-82-9)
- Trimebutine Impurity 29 (CAS CATO-C4X-185829)
- 4-Methyl-7-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one (CAS 141068-80-6)
- 3-Chloro-2-(m-tolyloxy)aniline (CAS 937604-51-8)
- Uremic Pentapeptide (CAS 71494-20-7)
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