4-(Ethoxycarbonyl)bicyclo[2.2.2]octane-1-carboxylic acid CAS 834-50-4
| CAS No. | 834-50-4 |
| Molecular Formula | C12H18O4 |
| Molecular Weight | 226.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(Ethoxycarbonyl)bicyclo[2.2.2]octane-1-carboxylic acid (CAS 834-50-4) is a high-purity analytical reference standard with the molecular formula C12H18O4 and a molecular weight of 226.27 g/mol.
The molecular framework of 4-(Ethoxycarbonyl)bicyclo[2.2.2]octane-1-carboxylic acid (C12H18O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 4-(Ethoxycarbonyl)bicyclo[2.2.2]octane-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H18O4 |
| Molecular Weight | 226.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Ethoxycarbonyl Standards
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Recommended Standards
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- (E)-4-(Phenyldiazenyl)benzoic Acid (CAS 37790-20-8)
- 2-[2-(4-Phenylpiperazin-1-yl)ethyl]-2H,3H,4H-pyrido[3,2-b][1,4]oxazin-3-one (CAS 860651-26-9)
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- Steroidogenesis-Activator Polypeptide (rat) (H-8855.0500) (CAS 108563-23-1)
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