Benzoic Acid impurity 7 CAS 83432-87-5
| CAS No. | 83432-87-5 |
| Molecular Formula | C21H17N3O4 |
| Molecular Weight | 375.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Benzoic Acid impurity 7 (CAS 83432-87-5, C21H17N3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Benzoic Acid impurity 7 (C21H17N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Benzoic Acid impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H17N3O4 |
| Molecular Weight | 375.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 3 |
Related Benzoic Standards
- 2-Phenyl Benzoic Anhydride (CAS 33813-33-1)
- 1223397-11-2 Benzoic acid, 3-hydroxy-, 1,1'-(3-fluoro-1,2-phenylene) ester (CAS 1223397-11-2)
- (S)-Benzoic acid 7R-methyl-1R-(1R,4R,5-trimethyl-hex-2-enyl)-octahydro-inden-4-yl ester (CAS 68702-86-3)
- Benzoic acid, 4-[3-amino-1-oxo-3-[4-(pentyloxy)phenyl]-2-propen-1-yl]-, methyl ester (CAS 849371-69-3)
- Benzoic Acid impurity 5 (CAS CATO-C4X-28455)
- Benzoic acid, 4-[bis[(1,1-dimethylethoxy)carbonyl]amino]-2-chloro-, methyl ester (CAS 1196073-25-2)
- Benzoic Acid, 2,2'-(1,2-ethanediyl)bis[6-methoxy-,dimethylester] (CAS 365543-17-5)
- Benzoic acid, 5-methoxy-4-[3-(4-morpholinyl)propoxy]-2-nitro-, methyl ester (CAS 944833-62-9)
Recommended Standards
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- Bumetanide Impurity 41 (CAS 20532-06-3)
- Chenodeoxycholic Acid Impurity 5 (CAS 59132-31-9)
- 2,5-Dihydro-2,5-dimethoxy-2-dimethoxymethylfuran (CAS 59906-91-1)
- 1-(3-Cyclopentyl-1-methyl-1h-1,2,4-triazol-5-yl)-N-methylethan-1-amine (CAS 1343226-03-8)
- Stigmasterol (CAS 83-48-7)
- 4-((4,5-Dichloropyridin-3-yl)sulfonyl)morpholine (CAS 1352502-10-3)
- Tropolone Tosylate (CAS 38768-08-0)
- 2-Chloro-1-(2,5-difluorophenyl)propan-1-one (CAS 1016527-64-2)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
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