5-((Prop-2-yn-1-yloxy)methyl)-1,3-dihydroisobenzofuran CAS 83469-16-3
| CAS No. | 83469-16-3 |
| Molecular Formula | C12H12O2 |
| Molecular Weight | 188.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-((Prop-2-yn-1-yloxy)methyl)-1,3-dihydroisobenzofuran.
5-((Prop-2-yn-1-yloxy)methyl)-1,3-dihydroisobenzofuran (CAS 83469-16-3), molecular formula C12H12O2 and molecular weight 188.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-((Prop-2-yn-1-yloxy)methyl)-1,3-dihydroisobenzofuran (C12H12O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-((Prop-2-yn-1-yloxy)methyl)-1,3-dihydroisobenzofuran meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12O2 |
| Molecular Weight | 188.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
Related Prop Standards
- 3-Ethyl-4-(prop-2-yn-1-yloxy)benzaldehyde (CAS 1796574-10-1)
- 1-(2-(Prop-2-yn-1-yloxy)phenyl)propan-1-one (CAS 60505-20-6)
- 6-Prop-2-enoxy-2,3-dihydroinden-1-one (CAS 320574-74-1)
- N-(4-(Prop-2-yn-1-ylamino)phenyl)acetamide (CAS 1250418-28-0)
- 1-(Prop-2-yn-1-yl)-3-(o-tolyl)urea (CAS 1437385-02-8)
- 1-(Prop-2-yn-1-yl)-2-(thiophen-2-yl)-1h-imidazole (CAS 1249302-29-1)
- 2-(Prop-2-yn-1-ylthio)-1H-benzo[d]imidazole (CAS 24786-40-1)
- 2-(Prop-2-yn-1-ylthio)-2H-benzo[d]imidazole (CAS 474011-47-7)
Recommended Standards
- 4-methyltricyclo[6.2.1.0^{2,7}]undeca-4,9-diene-3,6-dione (CAS 70050-88-3)
- 5-(Phenylmethyl)-3-furanmethanol (CAS 20416-09-5)
- 4-Fluoro-2-methyl-1-(methylsulfonyl)benzene (CAS 828270-62-8)
- 5-(tert-Butoxy)-5-oxopentanoic Acid (CAS 63128-51-8)
- 2-Chloro-6-(piperidin-1-yl)benzaldehyde (CAS 933917-04-5)
- n1-(Furan-2-ylmethyl)-n3,n3,2,2-tetramethylpropane-1,3-diamine (CAS 1019603-95-2)
- Methyl 4-(chlorosulfonyl)thiophene-2-carboxylate (CAS 97272-03-2)
- 4-(Tert-butyl)-N-(2-(methylthio)pyrimidin-4-yl)benzamide (CAS 866155-04-6)
- 2-{[6-amino-3-cyano-5-(phenylcarbamoyl)pyridin-2-yl]sulfanyl}acetic acid (CAS 852389-13-0)
- 5-(Phenylamino)naphthalene-1-sulfonic acid (CAS 20096-52-0)
- 2-Allyl-3-hydroxy-4-methoxybenzaldehyde (CAS 16273-13-5)
- 4-(4-Iodo-1H-pyrazol-1-yl)butan-1-amine (CAS 1339224-94-0)
- (S)-6-acetamido-3-aminohexanoic acid (CAS 40139-10-4)
- Gastric Inhibitory Polypeptide (6-30) amide (human) (CAS 1139691-72-7)
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