7-Chloro-3-methyl-3H-imidazo[4,5-b]pyridine CAS 83472-64-4
| CAS No. | 83472-64-4 |
| Molecular Formula | C7H6ClN3 |
| Molecular Weight | 167.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 167.60 g/mol gives 7-Chloro-3-methyl-3H-imidazo[4,5-b]pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
7-Chloro-3-methyl-3H-imidazo[4,5-b]pyridine (CAS 83472-64-4) is a high-purity analytical reference standard with the molecular formula C7H6ClN3 and a molecular weight of 167.60 g/mol.
Owing to a nitrile group, chlorine substitution, an aromatic ring system, 7-Chloro-3-methyl-3H-imidazo[4,5-b]pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 167.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6ClN3 |
| Molecular Weight | 167.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 4-Chloro-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1000340-38-4)
- 6-Chloro-1H-pyrrolo[2,3-b]pyridin-4-amine (CAS 1000340-80-6)
- 5-Chloro-1H-pyrrolo[3,2-b]pyridin-7-amine (CAS 1000577-90-1)
- 5-Chloro-1H-indazol-6-amine (CAS 100960-35-8)
- 3-chloro-6-methyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1020036-37-6)
- 7-Chloro-1H-benzo[d]imidazol-5-amine (CAS 10597-54-3)
- 6-Chloro-1H-benzo[d]imidazol-4-amine (CAS 10597-55-4)
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Recommended Standards
- 7-Chloro-2-methylpyrazolo[1,5-a]pyrimidine (CAS 954422-25-4)
- 7-Chloro-5-methyl-3H-imidazo[4,5-b]pyridine (CAS 860258-62-4)
- 7-Chloro-2-methylimidazo[4,5-c]pyridine (CAS 929074-44-2)
- 8-Chloro-2-methylimidazo[1,2-a]pyrazine, 97% (CAS 85333-43-3)
- Lipoamido-PEG3-OH (CAS 1342764-64-0)
- 3-(1-Isobutyrylpiperidin-4-yl)indolin-2-one (CAS 1790462-43-9)
- 2-(tert-Butyl)-6-nitroindoline (CAS 873055-08-4)
- N-Butyl-3-methoxy-2-propyl-2H-indazole-6-carboxamide (CAS 919107-91-8)
- (R)-1-Boc-3-(Aminomethyl)piperidine (CAS 140645-23-4)
- Tert-butyl ((5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl)methyl)carbamate (CAS 1053656-55-5)
- (2E)-3-(2,5-Dimethoxyphenyl)-1-(2-methylphenyl)prop-2-en-1-one (CAS 1354941-48-2)
- (2R,4S)-tert-butyl 4-amino-2-(4-chlorobenzyl)piperidine-1-carboxylate (CAS 2306253-85-8)
- tert-Butyl ((1,3-dioxolan-2-yl)methyl)carbamate (CAS 773095-22-0)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
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