1-(5-Fluoro-1H-indol-3-yl)-2,2-dimethylpropan-1-one CAS 835-44-9
| CAS No. | 835-44-9 |
| Molecular Formula | C13H14FNO |
| Molecular Weight | 219.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(5-Fluoro-1H-indol-3-yl)-2,2-dimethylpropan-1-one (CAS 835-44-9) is a high-purity analytical reference standard with the molecular formula C13H14FNO and a molecular weight of 219.25 g/mol.
The molecular framework of 1-(5-Fluoro-1H-indol-3-yl)-2,2-dimethylpropan-1-one (C13H14FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 1-(5-Fluoro-1H-indol-3-yl)-2,2-dimethylpropan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14FNO |
| Molecular Weight | 219.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
- N-(2-fluoro-5-methylbenzyl)-1-(furan-2-yl)methanamine (CAS 1249727-53-4)
- 4-Fluoro-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester (CAS 1260772-97-1)
- 8-Fluoro-3-isopropyl-2-methylquinolin-4-ol (CAS 1343879-97-9)
- 5-Fluoro-1-isopropyl-7-methyl-1H-indole-3-carbaldehyde (CAS 1350760-92-7)
- (3-Fluoro-4-methylphenyl)(1-methyl-1H-pyrrol-2-yl)methanol (CAS 1443350-56-8)
- (4-Fluoro-1-methyl-1H-pyrrol-2-yl)(m-tolyl)methanol (CAS 1443350-62-6)
- (5-Fluoro-2-methylphenyl)(1-methyl-1H-pyrrol-2-yl)methanol (CAS 1443350-68-2)
- 1-(3-Fluoro-4-methoxyphenyl)cyclopentanecarbonitrile (CAS 1521161-09-0)
Recommended Standards
- [1-(4-Fluorophenyl)-2,5-dimethyl-1h-pyrrol-3-yl]methanol (CAS 676339-59-6)
- 2-(Tert-butyl)-5-fluoro-1H-indole-3-carbaldehyde (CAS 588670-57-9)
- (S)-tert-Butyl 3-fluoro-3-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 2089671-54-3)
- 2-(Tert-butyl)-7-fluoro-1H-indole-3-carbaldehyde (CAS 586949-71-5)
- tert-Butyl N-(2-methylazetidin-3-yl)carbamate (CAS 1824525-92-9)
- 4,5-Bis(4-bromophenyl)-1H-imidazole (CAS 100965-13-7)
- 3,6-Dibromo-1,2,4,5-benzenetetramine (CAS 1443122-18-6)
- (+)-Biotin-PEG3-acid (CAS 252881-76-8)
- 2-(Difluoromethoxy)-2'-(trifluoromethoxy)-3-(trifluoromethyl)biphenyl (CAS 1261558-89-7)
- 6,6-Dimethyl-4,5,6,7-tetrahydro-1,3-benzothiazol-2-amine (CAS 79932-22-2)
- 5-(N,N-dimethylaminocarbonyl)-2-methoxyphenylboronic acid (CAS 945770-78-5)
- 4-Amino-1,2-dimethylpiperidine (CAS 89850-92-0)
- 8-oxa-5-azaspiro[3.5]nonan-6-one (CAS 1785379-16-9)
- [His]1-Acetylated Semaglutide (CAS CATO-C4X-2226219)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com