Diethyl (1,1-difluoro-2-hydroxy-2-phenylethyl)phosphonate CAS 83567-77-5
| CAS No. | 83567-77-5 |
| Molecular Formula | C12H17F2O4P |
| Molecular Weight | 294.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Diethyl (1,1-difluoro-2-hydroxy-2-phenylethyl)phosphonate.
CATO supplies Diethyl (1,1-difluoro-2-hydroxy-2-phenylethyl)phosphonate (CAS 83567-77-5), a certified reference material (molecular formula C12H17F2O4P, MW 294.23 g/mol) for analytical method development and quality control.
Structurally, Diethyl (1,1-difluoro-2-hydroxy-2-phenylethyl)phosphonate (C12H17F2O4P) contains a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 294.23 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17F2O4P |
| Molecular Weight | 294.23 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
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Recommended Standards
- 8-Methoxy-3-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 230295-08-6)
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- 6-Methoxy-3-(4-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 289651-70-3)
- 2-((4,6-Dimethoxypyrimidin-2-yl)oxy)-6-fluorobenzoic acid (CAS 113761-79-8)
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- Alpha-(trifluoromethyl)-2-hydroxy-5-(trifluoromethyl)benzyl amine (CAS 1337138-63-2)
- 2-Bromo-N-cyclopropylaniline (CAS 1418013-99-6)
- 4-Hydroxyfuran-2(5H)-one (CAS 541-57-1)
- Pcb No. 130 (CAS 52663-66-8)
- n-((5-Bromothiophen-2-yl)methyl)-4-methoxybutan-1-amine (CAS 1250550-40-3)
- 5-(Pyridin-4-yl)furan-2-carboxylic acid hydrochloride (CAS 222986-72-3)
- 1-(Tert-butyl) 2-ethyl 2-methylpyrrolidine-1,2-dicarboxylate (CAS 1358782-35-0)
- 2-(5-chlorothiophen-2-yl)-6-methoxyquinoline-4-carboxylic acid (CAS 897565-19-4)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
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