Loxoprofen Impurity 20 CAS 83599-40-0
| CAS No. | 83599-40-0 |
| Molecular Formula | C15H20O3 |
| Molecular Weight | 248.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Loxoprofen Impurity 20 (CAS 83599-40-0) is a certified pharmaceutical impurity reference standard with the molecular formula C15H20O3 and a molecular weight of 248.32 g/mol.
The molecular framework of Loxoprofen Impurity 20 (C15H20O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Loxoprofen Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H20O3 |
| Molecular Weight | 248.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
Related Loxoprofen Standards
- Loxoprofen Impurity 112 (CAS 88378-21-6)
- Loxoprofen Impurity 68 (CAS 83648-76-4)
- Loxoprofen Impurity 96 (CAS CATO-C4X-148896)
- Loxoprofen Impurity 97 (CAS CATO-C4X-148897)
- Loxoprofen-d3 (CAS CATO-C4X-1488102)
- Loxoprofen-d4 (CAS 68767-14-6 (non-labelled))
- Loxoprofen Impurity 147 (CAS CATO-C4X-1488147)
- Loxoprofen Impurity 148 (CAS CATO-C4X-1488148)
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