4-(4-Chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol hydrochloride CAS 83706-51-8
| CAS No. | 83706-51-8 |
| Molecular Formula | C12H13ClF3NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 316.14 g/mol gives 4-(4-Chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(4-Chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol hydrochloride (CAS 83706-51-8), molecular formula C12H13ClF3NOHCl and molecular weight 316.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(4-Chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol hydrochloride (C12H13ClF3NOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-Chloro-3-(trifluoromethyl)phenyl)piperidin-4-ol hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13ClF3NO HCl |
| Molecular Weight | 316.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- Ethyl 5-bromo-1-(propan-2-yl)-1H-imidazole-4-carboxylate (CAS 2113668-54-3)
- 2-((5-(2-Bromophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(3-chloro-2-methylphenyl)acetamide (CAS 493003-17-1)
- O-(1-(3-(Trifluoromethyl)phenyl)ethyl)hydroxylamine (CAS 166315-81-7)
- 4-Bromo-1-(but-3-en-1-yl)-1H-pyrazole (CAS 1343985-69-2)
- tert-Butyl 6-(bromomethyl)picolinate (CAS 1332367-16-4)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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