5-(2-Nitrophenyl)-3H-1,3,4-oxadiazol-2-one CAS 83725-79-5
| CAS No. | 83725-79-5 |
| Molecular Formula | C8H5N3O4 |
| Molecular Weight | 207.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(2-Nitrophenyl)-3H-1,3,4-oxadiazol-2-one (C8H5N3O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 5-(2-Nitrophenyl)-3H-1,3,4-oxadiazol-2-one (CAS 83725-79-5), a certified reference material (molecular formula C8H5N3O4, MW 207.14 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(2-Nitrophenyl)-3H-1,3,4-oxadiazol-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5N3O4 |
| Molecular Weight | 207.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 3 |
Related Nitrophenyl Standards
- 3-(3-nitrophenyl)-4,5-dihydro-1,2,4-oxadiazol-5-one (CAS 24011-15-2)
- 3-(4-Nitrophenyl)-4,5-dihydro-1,2,4-oxadiazol-5-one (CAS 19932-97-9)
- 5-(3-Nitrophenyl)-3H-1,3,4-oxadiazol-2-one (CAS 83725-80-8)
- 5-(4-Nitrophenyl)-1,3,4-oxadiazol-2-ol (CAS 41125-77-3)
- 1608-36-2 3-(P-NITROPHENYL)-2-PROPENOIC ACID, METHYL ESTER NSC-1323 NSC1323 (CAS 1608-36-2)
- Methyl 3-(3-nitrophenyl)acrylate (CAS 1664-59-1)
- (E)-3-(4-Nitrophenyl)but-2-enoic acid (CAS 179174-16-4)
- 1-(2-Nitrophenyl)butane-1,3-dione (CAS 5463-78-5)
Recommended Standards
- 4-Nitrobenzofuran-2-carboxylic acid (CAS 69604-06-4)
- 4-Nitro-1H-indazole-6-carboxylic acid (CAS 885519-71-1)
- 4-nitro-1H-indazole-3-carboxylic acid (CAS 885521-31-3)
- 5-Amino-6-Nitroisoindoline-1,3-dione (CAS 59827-85-9)
- 5-Chloro-2-hydroxybenzohydrazide (CAS 5022-48-0)
- 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-carbonitrile (CAS 942070-34-0)
- 1,6-Dimethyl-2-oxo-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,2-dihydropyridine-3-carboxylic acid methyl ester (CAS 1960432-44-3)
- Aurofusarin (CAS 13191-64-5)
- 207596-32-5 Palladium dinitrate hydrate Palladium nitrate hydrate Palladium(II) nitrate hydrate Palladous nitrate hydrate (CAS 207596-32-5)
- Tert-butyl (2-(3-chlorophenyl)propan-2-yl)carbamate (CAS 1332765-58-8)
- 3-((1,1-Dioxidothietan-3-yl)amino)-2,2-dimethylpropanamide (CAS 1857197-22-8)
- 2-(4-Fluoro-3-methylphenyl)propan-2-ol (CAS 1267002-57-2)
- (R)-4-Benzyloxazolidine-2-thione (CAS 190970-58-2)
- Custom peptides (CAS CATO-CPTD788509)
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