2-(6-Chloro-4-oxoquinazolin-3(4H)-yl)acetic acid CAS 83798-86-1

Purity 97%+In StockPharmaceutical Standards
CAS No.83798-86-1
Molecular FormulaC10H7ClN2O3
Molecular Weight238.63 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(6-Chloro-4-oxoquinazolin-3(4H)-yl)acetic acid CAS 83798-86-1 chemical structure

Description

The occurrence of 2-(6-Chloro-4-oxoquinazolin-3(4H)-yl)acetic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(6-Chloro-4-oxoquinazolin-3(4H)-yl)acetic acid (CAS 83798-86-1) is a high-purity analytical reference standard with the molecular formula C10H7ClN2O3 and a molecular weight of 238.63 g/mol.

2-(6-Chloro-4-oxoquinazolin-3(4H)-yl)acetic acid (C10H7ClN2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H7ClN2O3
Molecular Weight238.63 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1980
Halogen ContentCl-containing
Nitrogen Atoms2

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