(E)-N'-(4-hydroxybenzylidene)isonicotinohydrazide CAS 840-81-3
| CAS No. | 840-81-3 |
| Molecular Formula | C13H11N3O2 |
| Molecular Weight | 241.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-N'-(4-hydroxybenzylidene)isonicotinohydrazide.
(E)-N'-(4-hydroxybenzylidene)isonicotinohydrazide (CAS 840-81-3) is a high-purity analytical reference standard with the molecular formula C13H11N3O2 and a molecular weight of 241.25 g/mol.
(E)-N'-(4-hydroxybenzylidene)isonicotinohydrazide (C13H11N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-N'-(4-hydroxybenzylidene)isonicotinohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H11N3O2 |
| Molecular Weight | 241.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Recommended Standards
- (E)-1-benzylidene-2-(4-nitrophenyl)hydrazine (CAS 33786-33-3)
- 1-((Furan-2-ylmethylene)amino)-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 61296-00-2)
- (3-(4-(Trifluoromethyl)phenyl)bicyclo[1.1.1]Pentan-1-yl)methanamine (CAS 2227205-03-8)
- 1-(4-Methoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 925006-60-6)
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