6-Nitro-1,3-dihydrobenzo[c]isothiazole 2,2-dioxide CAS 841476-43-5

Description

The molecular framework of 6-Nitro-1,3-dihydrobenzo[c]isothiazole 2,2-dioxide (C7H6N2O4S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

6-Nitro-1,3-dihydrobenzo[c]isothiazole 2,2-dioxide (CAS 841476-43-5) is a high-purity analytical reference standard with the molecular formula C7H6N2O4S and a molecular weight of 214.20 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-Nitro-1,3-dihydrobenzo[c]isothiazole 2,2-dioxide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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