(E)-1-Acetyl-N-(acetyloxy)-α-(5-fluoro-2-hydroxyphenyl)-4-piperidinemethanimine CAS 84163-52-0
| CAS No. | 84163-52-0 |
| Molecular Formula | C16H19FN2O4 |
| Molecular Weight | 322.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-1-Acetyl-N-(acetyloxy)-α-(5-fluoro-2-hydroxyphenyl)-4-piperidinemethanimine is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (E)-1-Acetyl-N-(acetyloxy)-α-(5-fluoro-2-hydroxyphenyl)-4-piperidinemethanimine (CAS 84163-52-0), a certified reference material (molecular formula C16H19FN2O4, MW 322.33 g/mol) for analytical method development and quality control.
(E)-1-Acetyl-N-(acetyloxy)-α-(5-fluoro-2-hydroxyphenyl)-4-piperidinemethanimine (C16H19FN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H19FN2O4 |
| Molecular Weight | 322.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- (E)-[(6-Fluoropyridin-2-yl)oxy][1-(4-phenoxyphenyl)ethylidene]amine (CAS 338786-61-1)
- (R)-2-((tert-butoxycarbonyl)amino)-3-(6-fluoro-1H-indol-3-yl)propanoic acid (CAS 320581-69-9)
- 4-Fluoro-N-(4-(2-oxopyridin-1(2H)-yl)benzyl)benzamide (CAS 1956390-04-7)
- (S)-2-((tert-butoxycarbonyl)amino)-3-(5-fluoro-1H-indol-3-yl)propanoic acid (CAS 53478-53-8)
- 5-(3,4-Dichlorophenyl)-3-methyl-5-oxopentanoic acid (CAS 845781-38-6)
- Ethyl 2-((3-isopropoxyphenyl)thio)-2-oxoacetate (CAS 1443309-51-0)
- 3-((1-Methyl-1H-pyrazol-5-yl)methoxy)propanoic acid (CAS 1172964-34-9)
- pyrazolo[1,5-b]pyridazin-6-ol (CAS 2411637-09-5)
- 3,6-Diphenyl-N-(propan-2-yl)-1,2,4-triazin-5-amine (CAS 339013-13-7)
- 1-(5-Ethyl-1,3,4-thiadiazol-2-yl)piperidine-2,6-dione (CAS 378200-99-8)
- 2-(2-(Trifluoromethyl)furan-3-yl)acetamide (CAS 1330753-84-8)
- 2-(Difluoromethyl)-5-fluoro-3-hydroxy-6-methylpyridine (CAS 1805502-85-5)
- Dimethindene Maleate (CAS 3614-69-5)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
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