5-(chloromethyl)-2,3-dihydro-1,3,4-thiadiazol-2-one CAS 84352-71-6
| CAS No. | 84352-71-6 |
| Molecular Formula | C3H3ClN2OS |
| Molecular Weight | 150.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(chloromethyl)-2,3-dihydro-1,3,4-thiadiazol-2-one.
CATO supplies 5-(chloromethyl)-2,3-dihydro-1,3,4-thiadiazol-2-one (CAS 84352-71-6), a certified reference material (molecular formula C3H3ClN2OS, MW 150.59 g/mol) for analytical method development and quality control.
The molecular framework of 5-(chloromethyl)-2,3-dihydro-1,3,4-thiadiazol-2-one (C3H3ClN2OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H3ClN2OS |
| Molecular Weight | 150.59 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related chloromethyl Standards
- 1-(Chloromethyl)-4-ethynylbenzene (CAS 10601-98-6)
- 2-(Chloromethyl)-3-fluorothiophene (CAS 1227590-39-7)
- 2-(Chloromethyl)-4,4-dimethyl-1,3-dioxolane (CAS 126910-65-4)
- 2-(chloromethyl)-5-fluoro-thiophene (CAS 1379689-80-1)
- Chloromethyl 2-methylbutanoate (CAS 82504-44-7)
- Chloromethyl 3-methylbutanoate (CAS 82504-50-5)
- Chloromethyl pentanoate (CAS 77877-94-2)
- 4-(Chloromethyl)-2,2-dimethyl-1,3-dioxolane (CAS 4362-40-7)
Recommended Standards
- 3-Chloro-4-methoxy-1,2,5-thiadiazole (CAS 5728-16-5)
- (4-chlorooxan-4-yl)methanol (CAS 100506-90-9)
- (5-Chloro-1,3,4-thiadiazol-2-yl)methanol (CAS 912669-58-0)
- (5-Chloro-1,2,3-thiadiazol-4-yl)methanol (CAS 926207-15-0)
- (E)-Octadec-9-en-1-amine hydrochloride (CAS 41130-29-4)
- HIV Protease Substrate IV (CAS 128340-47-6)
- [1,2,4]triazolo[4,3-a]pyridin-6-ylboronic acid (CAS 1588769-41-8)
- Saxagliptin Impurity 33 (CAS 2173146-02-4)
- 4-((5-Chloro-1-(3,5-dichlorophenyl)-6-oxo-1,6-dihydropyridazin-4-yl)oxy)-3-methoxybenzaldehyde (CAS 881584-90-3)
- 1-chloro-3-cyclopropylbutan-2-one (CAS 1555324-77-0)
- 2-(2-Ethoxyphenyl)piperidine, hydrochloride (CAS 1177349-47-1)
- 2-[2-(4-methoxyphenyl)-1,3-oxazol-4-yl]acetonitrile (CAS 949980-19-2)
- 2,2':4',4'':2'',2'''-Quaterpyridine, 6',6''-di-2-pyridinyl- (CAS 128143-86-2)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
Why CATO?
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