4-(1H-Benzimidazol-2-yl)-1-(4-methylphenyl)pyrrolidin-2-one CAS 843624-76-0
| CAS No. | 843624-76-0 |
| Molecular Formula | C18H17N3O |
| Molecular Weight | 291.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 291.35 g/mol gives 4-(1H-Benzimidazol-2-yl)-1-(4-methylphenyl)pyrrolidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(1H-Benzimidazol-2-yl)-1-(4-methylphenyl)pyrrolidin-2-one (CAS 843624-76-0) is a high-purity analytical reference standard with the molecular formula C18H17N3O and a molecular weight of 291.35 g/mol.
The molecular framework of 4-(1H-Benzimidazol-2-yl)-1-(4-methylphenyl)pyrrolidin-2-one (C18H17N3O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(1H-Benzimidazol-2-yl)-1-(4-methylphenyl)pyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17N3O |
| Molecular Weight | 291.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
Related H Standards
- 4-(1H-Benzimidazol-2-yl)-1-(3-methylphenyl)pyrrolidin-2-one (CAS 573931-42-7)
- 6-Phenyl-benzimidazol(1,2-c)quinazoline (CAS 28381-92-2)
- 4-(1H-Benzimidazol-2-yl)-1-cyclohexylpyrrolidin-2-one (CAS 942810-98-2)
- 2-(1H-benzimidazol-2-yl)-N-(4-fluorobenzyl)acetamide (CAS 730950-14-8)
- 1H-Benzimidazol-2-ylferrocene (CAS 34830-88-1)
- 2-(1H-1,3-Benzimidazol-2-ylsulfanyl)-1-(4-chlorophenyl)-1-ethanone (CAS 22794-89-4)
- 4-(1H-Benzimidazol-2-yl)-1-(4-ethylphenyl)pyrrolidin-2-one (CAS 847394-57-4)
- 1-(1H-Benzimidazol-2-yl)-3-phenyl-1H-pyrazol-5-ol (CAS 516455-58-6)
Recommended Standards
- 4-(1H-Benzo[d]imidazol-2-yl)-1-(o-tolyl)pyrrolidin-2-one (CAS 491874-24-9)
- 4-((4-(4-Methylpiperazin-1-yl)phenyl)amino)-4-oxobutanoic acid (CAS 724455-62-3)
- 4-(1H-Benzo[d]imidazol-2-yl)-1-benzylpyrrolidin-2-one (CAS 847396-32-1)
- 3-Nitro-N-octylimidazo[1,2-b]pyridazin-6-amine (CAS 37990-80-0)
- 3-(3-Methylbutyl)cyclopentan-1-amine (CAS 1339611-37-8)
- 1-Cyclopropyl-2-phenylethan-1-ol (CAS 18729-52-7)
- 3-Bromoquinoline-8-carbonitrile (CAS 1699370-11-0)
- 2-Chloro-3-(difluoromethyl)-5-fluoropyridin-4-amine (CAS 1806807-02-2)
- 4-[(3,5-dimethylpiperidin-1-yl)sulfonyl]benzene-1-sulfonyl chloride (CAS 1258650-42-8)
- 4-Bromo-3,6-dimethoxypyridazine (CAS 262353-33-3)
- 2-bromo-1-(1-methyl-1H-imidazol-2-yl)ethanone (CAS 750556-81-1)
- 2-Benzoyl-1-(4-methoxybenzyl)-1,2-dihydroisoquinoline-1-carbonitrile (CAS 61010-37-5)
- 4-Ethyl-3-(1-oxoisoindolin-2-yl)hexanoic acid (CAS 866144-54-9)
- D-Pro31-Tirzepatide (CAS CATO-CPTD788905)
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