(3-Chloro-5-fluorophenyl)(3,4-dichlorophenyl)methanone CAS 844885-33-2
| CAS No. | 844885-33-2 |
| Molecular Formula | C13H6Cl3FO |
| Molecular Weight | 303.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3-Chloro-5-fluorophenyl)(3,4-dichlorophenyl)methanone (CAS 844885-33-2) is a high-purity analytical reference standard with the molecular formula C13H6Cl3FO and a molecular weight of 303.54 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, (3-Chloro-5-fluorophenyl)(3,4-dichlorophenyl)methanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 303.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H6Cl3FO |
| Molecular Weight | 303.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (3-Chloro-4-fluorophenyl)(3,5-dichlorophenyl)methanone (CAS 951890-36-1)
- (4-Chloro-3-fluorophenyl)(3,5-dichlorophenyl)methanone (CAS 951890-82-7)
- 4-Chloro-3-iodo-2-methylquinoline (CAS 1033931-93-9)
- 4-Chloro-3-iodo-6-methylquinoline (CAS 1431364-43-0)
- 2-Chloro-4-iodo-nicotinic acid methyl ester (CAS 185041-05-8)
- 6-chloro-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1935368-77-6)
- 4-Chloro-7-iodo-6-methylquinoline (CAS 507242-73-1)
- 7-Chloro-4-iodo-3-methylisoquinoline (CAS 2073126-57-3)
Recommended Standards
- 6'-bromo-8'-chloro-1'H-spiro[cyclobutane-1,3'-imidazo[1,5-a]pyridine]-1',5'(2'H)-dione (CAS 1849592-10-4)
- 1-(8-Bromo-4-chloro-7-methylpyrazolo[1,5-a][1,3,5]triazin-2-yl)cyclopropan-1-ol (CAS 2387601-55-8)
- Ethyl 7-bromo-5-chlorobenzofuran-2-carboxylate (CAS 1823331-46-9)
- 3-Fluoro-3,4,4-trichlorobenzophenone (CAS 951890-80-5)
- 4-(Bromomethyl)-1-methyl-2-oxabicyclo[2.2.2]octane (CAS 2137033-85-1)
- 1-[Chloro(difluoro)methoxy]-3-fluoro-5-(trifluoromethyl)benzene (CAS 1417567-13-5)
- 1-Fluoro-3-(trifluoromethyl)-4-(3,3,3-trifluoropropoxy)benzene (CAS 1779122-36-9)
- Ethyl (3,5-dibromo-4-(difluoromethoxy)phenyl)carbamate (CAS 84970-92-3)
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- Methyl 2-azaspiro[3.4]Octane-1-carboxylate hydrochloride (CAS 2031258-52-1)
- Desethyl Amiodarone-D4 N-nitroso (CAS CATO-C4X-142547)
- Belumosudil Impurity 63 (CAS CATO-C4X-298863)
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