4-[(Piperidin-4-yl)oxy]piperidine-1-carboxylic acid tert-butyl ester CAS 845305-83-1
| CAS No. | 845305-83-1 |
| Molecular Formula | C15H28N2O3 |
| Molecular Weight | 284.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-[(Piperidin-4-yl)oxy]piperidine-1-carboxylic acid tert-butyl ester.
4-[(Piperidin-4-yl)oxy]piperidine-1-carboxylic acid tert-butyl ester (CAS 845305-83-1), molecular formula C15H28N2O3 and molecular weight 284.39 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[(Piperidin-4-yl)oxy]piperidine-1-carboxylic acid tert-butyl ester (C15H28N2O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H28N2O3 |
| Molecular Weight | 284.39 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Piperidin Standards
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- trans-1-[(tert-Butoxy)carbonyl]-4-phenylpiperidine-3-carboxylic acid (CAS 170838-49-0)
- 2H-Benzo[b][1,4]thiazin-3(4H)-one 1,1-dioxide (CAS 2799-68-0)
- 2-(3,5-Dimethylisoxazol-4-yl)acetohydrazide (CAS 934172-43-7)
- Ethyl 5-hydroxy-2-methyl-1-phenyl-1H-indole-3-carboxylate (CAS 5564-29-4)
- 3-(Piperazin-1-ylmethyl)furan-2-carboxylic acid dihydrochloride (CAS 1258650-94-0)
- 7-bromopyrimido[1,2-a]benzimidazole (CAS 1446093-78-2)
- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
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