5-Fluoro-1-methylspiro[indoline-3,4'-piperidin]-2-one CAS 845552-97-8
| CAS No. | 845552-97-8 |
| Molecular Formula | C13H15FN2O |
| Molecular Weight | 234.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Fluoro-1-methylspiro[indoline-3,4'-piperidin]-2-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Fluoro-1-methylspiro[indoline-3,4'-piperidin]-2-one (CAS 845552-97-8), molecular formula C13H15FN2O and molecular weight 234.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Fluoro-1-methylspiro[indoline-3,4'-piperidin]-2-one (C13H15FN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Fluoro-1-methylspiro[indoline-3,4'-piperidin]-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H15FN2O |
| Molecular Weight | 234.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-Fluoro-2-(trans-4-hydroxycyclohexylamino)-benzonitrile (CAS 1008414-99-0)
- 3-Fluoro-4-[4-(hydroxymethyl)piperidin-1-yl]benzonitrile (CAS 1157060-75-7)
- 5-Fluoro-1'-methylspiro[indoline-3,4'-piperidin]-2-one (CAS 1198283-83-8)
- 6-Fluoro-2-(piperidin-4-yl)isoindolin-1-one (CAS 1439902-96-1)
- 6-fluoro-2-(piperidin-4-ylmethyl)-1,3-benzoxazole (CAS 1521612-18-9)
- 6'-Fluoro-4'-methoxy-spiro[cyclopentane-1,2'-indane]-1'-one (CAS 1612855-13-6)
- (s)-4-Fluoro-2-(piperidin-3-yl)isoindolin-1-one (CAS 1787444-98-7)
- 4-((5-Fluoro-1H-indol-3-yl)methyl)morpholine (CAS 1892733-57-1)
Recommended Standards
- 5-[4-(prop-2-en-1-yloxy)phenyl]-1,3,4-oxadiazole-2-thiol (CAS 331002-91-6)
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- 5-[4-(Methylsulfanyl)phenyl]-2-furoic acid (CAS 893734-62-8)
- 6-(2-Methoxyphenyl)-2-thioxo-2,3-dihydropyrimidin-4(1{H})-one (CAS 886140-11-0)
- Ethyl 4-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1146214-96-1)
- N1-(2,4-dichlorophenyl)oxalamide (CAS 17738-96-4)
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- 8-Chloro-2-(3-hydroxypropyl)isoquinolin-1-one (CAS 2120817-40-3)
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- (2E)-2-(2-furylmethylene)cyclohexanone (CAS 10496-51-2)
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