4-Amino-4'-(trifluoromethyl)[1,1'-biphenyl]-3-carboxylic acid CAS 845681-72-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Amino-4'-(trifluoromethyl)[1,1'-biphenyl]-3-carboxylic acid.

4-Amino-4'-(trifluoromethyl)[1,1'-biphenyl]-3-carboxylic acid (CAS 845681-72-3) is a high-purity analytical reference standard with the molecular formula C14H10F3NO2 and a molecular weight of 281.23 g/mol.

Structurally, 4-Amino-4'-(trifluoromethyl)[1,1'-biphenyl]-3-carboxylic acid (C14H10F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 281.23 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Amino-4'-(trifluoromethyl)[1,1'-biphenyl]-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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