1-(1H-Imidazol-2-yl)-1H-pyrazol-5(4H)-one CAS 845749-94-2
| CAS No. | 845749-94-2 |
| Molecular Formula | C6H6N4O |
| Molecular Weight | 150.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(1H-Imidazol-2-yl)-1H-pyrazol-5(4H)-one (CAS 845749-94-2) is a high-purity analytical reference standard with the molecular formula C6H6N4O and a molecular weight of 150.14 g/mol.
The molecular framework of 1-(1H-Imidazol-2-yl)-1H-pyrazol-5(4H)-one (C6H6N4O) is characterized by an amide group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 1-(1H-Imidazol-2-yl)-1H-pyrazol-5(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6N4O |
| Molecular Weight | 150.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
Related H Standards
- 4-(1H-Imidazol-2-yl)-1H-1,2,3-triazol-5-amine (CAS 719261-16-2)
- 3-(1H-imidazol-1-yl)-2-(methylamino)propanenitrile (CAS 1249173-00-9)
- (1H-Imidazol-1-yl)(1-methylcyclopropyl)methanone (CAS 134302-16-2)
- (1H-Imidazol-2-yl)(1-methylcyclopropyl)methanone (CAS 952200-98-5)
- 4-(1H-Imidazol-5-yl)-1,2,3,6-tetrahydropyridine (CAS 273218-94-3)
- 3-(1H-Imidazol-5-yl)-N-methylacrylamide (CAS 952732-78-4)
- 2-(1H-Imidazol-1-yl)thiazole (CAS 446287-13-4)
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Recommended Standards
- 1-((4H-1,2,4-Triazol-4-yl)methyl)-1H-1,2,4-triazole (CAS 785010-95-9)
- 1,2-Bis(dimethylphosphino)ethane (CAS 23936-60-9)
- [1,2,4]Triazolo[4,3-b]pyridazin-3-ylmethanol (CAS 88277-73-0)
- 1,2-Dihydropyrido[2,3-e][1,2,4]triazin-3(4H)-one (CAS 247144-93-0)
- Fovinaciclib (CAS 2146171-49-3)
- 8-Bromo-5-methyl-3,4-dihydronaphthalen-1(2H)-one (CAS 1260009-83-3)
- 4,4'-Diphenoxybenzophenone (CAS 14984-21-5)
- 2-Amino-1H-indole-3-carbaldehyde (CAS 55186-46-4)
- 6-(Aminomethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one hydrochloride (CAS 916211-06-8)
- 2‐{5‐[(1H‐1,2,4‐triazol‐1‐yl)methyl](3a,4,5,6,7,7a‐13C6)‐1H‐indol‐3‐yl}acetic acid (CAS 1316755-17-5)
- 3-Chloro-2,5-dimethylaniline (CAS 13711-24-5)
- 6-fluoro-5-methylpyridine-3-carboxylic acid (CAS 885267-35-6)
- N-[(6-chloropyridin-3-yl)methyl]-N-methylpropan-2-amine (CAS 1016688-73-5)
- D-[Thr]5-Semaglutide (CAS CATO-C4X-2226245)
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