4-tert-Butyl-3,4-difluorobenzophenone CAS 845781-01-3
| CAS No. | 845781-01-3 |
| Molecular Formula | C17H16F2O |
| Molecular Weight | 274.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-tert-Butyl-3,4-difluorobenzophenone (C17H16F2O) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-tert-Butyl-3,4-difluorobenzophenone (CAS 845781-01-3), molecular formula C17H16F2O and molecular weight 274.31 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-tert-Butyl-3,4-difluorobenzophenone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16F2O |
| Molecular Weight | 274.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Recommended Standards
- 4-Phenoxybenzophenone (CAS 6317-73-3)
- 5-((2-Isopropyl-5-methylphenoxy)methyl)furan-2-carboxylic acid (CAS 364746-27-0)
- 4-Methyl-3-(naphthalen-1-yl)isobenzofuran-1(3H)-one (CAS 86785-13-9)
- 5,8-Dihydroxy-2-(4-methylpentyl)naphthalene-1,4-dione (CAS 517-90-8)
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Why CATO?
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