5-(5-Chloro-2-thienyl)-3-methyl-5-oxovaleric acid CAS 845781-52-4
| CAS No. | 845781-52-4 |
| Molecular Formula | C10H11ClO3S |
| Molecular Weight | 246.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 5-(5-Chloro-2-thienyl)-3-methyl-5-oxovaleric acid (CAS 845781-52-4), a certified reference material (molecular formula C10H11ClO3S, MW 246.71 g/mol) for analytical method development and quality control.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 5-(5-Chloro-2-thienyl)-3-methyl-5-oxovaleric acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 246.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 5-(5-Chloro-2-thienyl)-3-methyl-5-oxovaleric acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11ClO3S |
| Molecular Weight | 246.71 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 6-chloro-N-(cyclopropylmethyl)pyridine-3-sulfonamide (CAS 1016689-89-6)
- 2-Chloro-1-(methyl-d3)-6-phenylimidazo(4,5-b)pyridine (CAS 1020719-30-5)
- 2-Chloro-4-(pyrrolidine-1-sulfonyl)pyridine (CAS 1179655-82-3)
- methyl 4-chloro-2-(pyrrolidin-1-yl)-1,3-thiaZole-5-carboxylate (CAS 1183743-41-0)
- (Z)-1-Chloro-2-(2-(4-fluorophenyl)prop-1-en-1-yl)benzene (CAS 1187311-54-1)
- Potassium 5-chloro-2-hydroxyÂbenzÂenesulfoÂnate (CAS 120161-43-5)
- 2-Chloro-N-cyclobutylpyridine-3-sulfonamide (CAS 1247365-21-4)
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Recommended Standards
- 5-(1,3-Dioxolan-2-yl)-2-thienyl octyl ketone (CAS 898771-94-3)
- 6-Methoxy-2,3-dihydro-1H-indene-5-sulfonyl chloride (CAS 88040-92-0)
- 4-Chloro-9H-thioxanthen-9-one (CAS 21908-85-0)
- Ethyl 2-((4-chlorophenyl)sulfinyl)acetate (CAS 91077-12-2)
- 5α-ANDROSTAN-17α-METHYL-3β, 17β-DIOL (CAS 641-83-8)
- Ergocalciferol EP Impurity A (CAS 51744-66-2)
- (E)-1-{[4-(benzyloxy)phenyl]methylidene}-2-(4-tert-butylphenyl)hydrazine (CAS 477863-00-6)
- 5-Bromo-2,6-dimethoxy-3-methylsulfanylpyridine (CAS 1879026-16-0)
- 1-(3-Bromo-4-fluorobenzyl)piperidine-3-carboxamide (CAS 331860-16-3)
- 2-Methylthiopyridine-5-carboxaldehyde (CAS 149805-95-8)
- 4-Bromo-N-((1-methyl-1h-pyrrol-2-yl)methyl)aniline (CAS 1040074-32-5)
- 7-Bromo-2,3-dihydrobenzo[b][1,4]dioxin-6-ol (CAS 1216307-76-4)
- Ethyl 2-(7-(4-fluorophenyl)-4-oxothieno[3,2-d]pyrimidin-3(4H)-yl)acetate (CAS 1357900-00-5)
- Exenatide (CAS 141758-74-9（free base）)
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