5-(4-Fluorophenyl)picolinic acid CAS 845826-99-5
| CAS No. | 845826-99-5 |
| Molecular Formula | C12H8FNO2 |
| Molecular Weight | 217.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-Fluorophenyl)picolinic acid (CAS 845826-99-5), molecular formula C12H8FNO2 and molecular weight 217.20 g/mol, is a CATO reference standard with documented purity and traceability.
5-(4-Fluorophenyl)picolinic acid (C12H8FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(4-Fluorophenyl)picolinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8FNO2 |
| Molecular Weight | 217.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 2-(4-Fluorophenyl)nicotinic acid (CAS 101419-78-7)
- 5-(3-Fluorophenyl)picolinic acid (CAS 1158763-55-3)
- 5-(2-Fluorophenyl)picolinic acid (CAS 1158763-56-4)
- 3-(4-Fluorophenyl)picolinic acid (CAS 1192608-90-4)
- 3-(4-Fluorophenyl)isonicotinic acid (CAS 1214348-98-7)
- 4-(3-Fluorophenyl)picolinic acid (CAS 1214349-18-4)
- 2-(3-Fluorophenyl)isonicotinic acid (CAS 1214350-69-2)
- 3-(3-Fluorophenyl)picolinic acid (CAS 1214360-08-3)
Recommended Standards
- 5-(2-Fluorophenyl)nicotinic Acid (CAS 705961-96-2)
- 5-(Methylsulfonyl)-2-nitrophenol (CAS 2637445-88-4)
- 4-Oxo-1-phenylphosphinane-3-carbonitrile (CAS 39767-81-2)
- 5-Amino-1-(6-fluoropyridin-3-yl)-3-methyl-1H-pyrazole-4-carbonitrile (CAS 2168407-99-4)
- (1r)-1-(2-Bromo-4-fluorophenyl)ethan-1-ol (CAS 704909-66-0)
- 130915-89-8 IL-1a (223-250) (human) MFCD00237122 (CAS 130915-89-8)
- 2-(3-(Pyridin-2-yl)-1H-pyrazol-1-yl)ethan-1-amine (CAS 1300038-57-6)
- Tos-Gly-OH (CAS 1080-44-0)
- tert-Butyl 3-oxo-2-phenyl-1-pyrrolidinecarboxylate (CAS 801282-28-0)
- Methyl 2-chloro-8-methylquinoline-3-carboxylate (CAS 773874-59-2)
- Gadoxetate Impurity 9 (CAS CATO-C4X-26189)
- 2-Methyl-5-(1H-pyrrol-1-yl)aniline (CAS 137352-77-3)
- Ethyl 6-(dimethylamino)hexanoate (CAS 2508-32-9)
- MOTS-c Peptide (CAS 1627580-64-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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