4-(Trifluoromethyl)-1,4,5,6-tetrahydropyridine-3-carbonitrile CAS 845866-48-0
| CAS No. | 845866-48-0 |
| Molecular Formula | C7H7F3N2 |
| Molecular Weight | 176.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(Trifluoromethyl)-1,4,5,6-tetrahydropyridine-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-(Trifluoromethyl)-1,4,5,6-tetrahydropyridine-3-carbonitrile (CAS 845866-48-0), a certified reference material (molecular formula C7H7F3N2, MW 176.14 g/mol) for analytical method development and quality control.
4-(Trifluoromethyl)-1,4,5,6-tetrahydropyridine-3-carbonitrile (C7H7F3N2) contains a nitrile group, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H7F3N2 |
| Molecular Weight | 176.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 2-Methyl-5-(trifluoromethyl)phenol (CAS 1017778-05-0)
- 4-Methyl-3-(trifluoromethyl)phenol (CAS 1017778-16-3)
- (3-(Trifluoromethyl)pyridin-4-yl)methanamine (CAS 1060801-91-3)
- 3-Methyl-2-(trifluoromethyl)phenol (CAS 106877-37-6)
- 5-Methyl-2-(trifluoromethyl)phenol (CAS 106877-38-7)
- 3-Methyl-4-(trifluoromethyl)phenol (CAS 106889-91-2)
- 3-Methyl-5-(trifluoromethyl)pyridin-4-amine (CAS 1101061-18-0)
- 4-Methyl-2-(trifluoromethyl)pyridin-3-amine (CAS 1211540-24-7)
Recommended Standards
- 4-(2,2,2-Trifluoroethyl)phenol (CAS 86571-21-3)
- 4-(Trifluoromethyl)benzyl Alcohol (CAS 349-95-1)
- 3-Methyl-5-(trifluoromethyl)pyridin-2-amine (CAS 945971-04-0)
- 4-Methoxybenzotrifluoride (CAS 402-52-8)
- 1-Benzyl-1H-indole-5-carbonitrile (CAS 80531-13-1)
- 1-(2,4-Difluorophenyl)urea (CAS 145602-64-8)
- Methyl 3-((4-formylphenoxy)methyl)benzoate (CAS 225942-73-4)
- 3-(4-Hydroxy-3,5-dimethylphenyl)acrylic acid (CAS 7733-57-5)
- 4-[4-(Dimethylamino)benzylidene]-2-methyl-1,3-oxazol-5(4H)-one (CAS 1787-23-1)
- Ethyl 2-(4-aminopiperazin-1-yl)acetate (CAS 158773-35-4)
- 2-(Ethyl(2-methoxybenzyl)amino)ethanol (CAS 104743-43-3)
- 2-Bromo-5-(2-(chloromethyl)butyl)thiophene (CAS 1481394-68-6)
- Benzyl 3-acetylpyrrolidine-1-carboxylate (CAS 848413-78-5)
- Peptide 74 (H-8545.0500) (CAS 132116-39-3)
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