1-Chloro-2-iodo-4-(trifluoromethoxy)benzene CAS 845866-91-3

Purity 97%+In StockPharmaceutical Standards
CAS No.845866-91-3
Molecular FormulaC7H3ClF3IO
Molecular Weight322.45 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Chloro-2-iodo-4-(trifluoromethoxy)benzene CAS 845866-91-3 chemical structure

Description

The occurrence of 1-Chloro-2-iodo-4-(trifluoromethoxy)benzene is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-Chloro-2-iodo-4-(trifluoromethoxy)benzene (CAS 845866-91-3), molecular formula C7H3ClF3IO and molecular weight 322.45 g/mol, is a CATO reference standard with documented purity and traceability.

1-Chloro-2-iodo-4-(trifluoromethoxy)benzene (C7H3ClF3IO) contains a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H3ClF3IO
Molecular Weight322.45 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF/Cl/I-containing

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