Etomidate Impurity 5 CAS 84711-26-2
| CAS No. | 84711-26-2 |
| Molecular Formula | C14H16N2O2S |
| Molecular Weight | 276.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Etomidate Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Etomidate Impurity 5 (CAS 84711-26-2), a pharmacopoeial impurity reference standard (molecular formula C14H16N2O2S, MW 276.35 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Etomidate Impurity 5 (C14H16N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H16N2O2S |
| Molecular Weight | 276.35 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Etomidate Standards
- Etomidate Impurity 23 (CAS 112421-33-7)
- Etomidate Impurity 31 (CAS CATO-C4X-188431)
- Etomidate Impurity 36 (CAS CATO-C4X-188436)
- Etomidate Impurity 47 (CAS CATO-C4X-188447)
- Etomidate Impurity 48 (CAS CATO-C4X-188448)
- Etomidate Impurity 75 (CAS 1567838-90-7)
- Etomidate impurity 59 (CAS CATO-C4X-188459)
- Etomidate impurity 53 (CAS CATO-C4X-188453)
Recommended Standards
- For-Met-Val-OH (CAS 29790-45-2)
- Fasudil Impurity 20 (CAS CATO-C4X-136520)
- N-(5-Methyl-[1,3,4]thiadiazol-2-yl)-2-p-tolylamino-propionamide (CAS 1008494-23-2)
- 4-amino-N-(2-phenylethyl)benzenesulfonamide 4-amino-N-phenethylbenzenesulfonamide 587850-67-7 (CAS 587850-67-7)
- Ketoprofen Impurity 49 (CAS 620-83-7)
- Dapagliflozin Impurity 68 (CAS 1103738-29-9)
- Rosuvastatin Impurity 227 (CAS CATO-C4X-1169227)
- 4-Methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid (CAS 269409-71-4)
- (S)-2-amino-3-(2,4,6-trifluorophenyl)propanoic acid (CAS 481660-72-4)
- 3-Amino-6-ethyl-N-(4-methoxyphenyl)-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 445269-08-9)
- 8-Chloroquinolin-3-amine (CAS 347146-21-8)
- (R)-2-(3-chloro-2-fluoro-6-(trifluoromethyl)phenyl)pyrrolidine (CAS 1213058-98-0)
- N-(5-amino-2-methoxyphenyl)-2-(4-ethylphenoxy)acetamide (CAS 1020054-67-4)
- Semaglutide impurity 51 (CAS CATO-C4X-222651)
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