Ethyl 5-Bromopyridine-3-acetate CAS 847375-33-1
| CAS No. | 847375-33-1 |
| Molecular Formula | C9H10BrNO2 |
| Molecular Weight | 244.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 5-Bromopyridine-3-acetate (CAS 847375-33-1), molecular formula C9H10BrNO2 and molecular weight 244.09 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 5-Bromopyridine-3-acetate (C9H10BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10BrNO2 |
| Molecular Weight | 244.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 4-Bromopyridine-2,6-dicarboxamide (CAS 668992-72-1)
- 5-Bromopyridine-2,4-dicarboxylic acid (CAS 118092-07-2)
- 3-Bromopyridine-2,4-dicarboxylic acid (CAS 1222184-73-7)
- 3-Bromopyridine-2,5-dicarboxylic acid (CAS 1260664-10-5)
- 4-Bromopyridine-2,6-dicarboxylic acid, 97% (CAS 162102-81-0)
- 3-Bromopyridine-2,6-dicarboxylic acid (CAS 316808-10-3)
- 5-Bromopyridine-2,3-dicarboxylic Acid (CAS 98555-51-2)
- 5-Bromopyridine-3,4-dicarboxylic acid (CAS 90325-36-3)
Recommended Standards
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- Ethyl n-(4-bromophenyl)carbamate (CAS 7451-53-8)
- 2-((3-Cyano-6-(thiophen-2-yl)pyridin-2-yl)thio)acetic acid (CAS 340807-55-8)
- 4-(4-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)morpholine (CAS 1684430-49-6)
- Ethyl 13-amino-2,3,5,6,8,9-hexahydrobenzo[b][1,4,7,10]tetraoxacyclododecine-12-carboxylate (CAS 1204386-13-9)
- Methyl 2-(3-hydroxypyrrolidin-1-yl)-5-(trifluoromethyl)benzoate (CAS 1956386-28-9)
- 3-Methyl-4,6-dioxo-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carbaldehyde (CAS 75088-58-3)
- n-Hexadecyltrimethylammonium-d42 Bromide (CAS 907216-28-8)
- alpha-(2-Aminophenyl)benzylamine (CAS 61057-85-0)
- Benzenecarbothioicacid,[(2-hydroxyphenyl)methylene]hydrazide,palladiumcomplex (CAS 132829-27-7)
- 3-Ethynylthiophene-2-carbaldehyde (CAS 221103-69-1)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
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