6-Chloro-2-(2,5-dimethylthien-3-yl)quinoline-4-carboxylic acid CAS 847503-13-3
| CAS No. | 847503-13-3 |
| Molecular Formula | C16H12ClNO2S |
| Molecular Weight | 317.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-2-(2,5-dimethylthien-3-yl)quinoline-4-carboxylic acid (CAS 847503-13-3), molecular formula C16H12ClNO2S and molecular weight 317.79 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloro-2-(2,5-dimethylthien-3-yl)quinoline-4-carboxylic acid (C16H12ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12ClNO2S |
| Molecular Weight | 317.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- N-(4-chloro-2-fluorophenyl)-1-phenylcyclopentane-1-carboxamide (CAS 1023531-97-6)
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- ((4-Chloro-2,5-dimethylphenyl)sulfonyl)-l-proline (CAS 345637-80-1)
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Recommended Standards
- 6-(tert-Butoxycarbonyl)-2-chloro-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid (CAS 2138373-28-9)
- 6-Chloro-2-(5-ethylthiophen-2-yl)quinoline-4-carboxylic acid (CAS 438215-52-2)
- 5-Chloro-N-(4-methoxynaphthalen-1-yl)thiophene-2-carboxamide (CAS 330678-00-7)
- 7-Chloro-8-methyl-2-(5-methylthiophen-2-yl)quinoline-4-carboxylic acid (CAS 588696-20-2)
- N1-(pyridazin-3-yl)ethane-1,2-diamine (CAS 193473-68-6)
- <I>N,N</I>-diethyl salicylamide (CAS 19311-91-2)
- Ethyl 4-amino-8-isopropylquinoline-3-carboxylate (CAS 1279202-45-7)
- N-(5-(Ethoxymethyl)-1,3,4-thiadiazol-2-yl)tetrahydrofuran-2-carboxamide (CAS 701239-54-5)
- 5-Amino-1-(hydrazonomethyl)-1H-pyrazole-4-carbonitrile (CAS 30433-65-9)
- (4-Amino-2-methylphenyl)(morpholino)methanone (CAS 869859-95-0)
- (4-Methylpyridin-2-yl)methanol hydrochloride (CAS 1087766-33-3)
- 2-(Methoxymethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1430401-34-5)
- Methyl 5-((sec-butylamino)methyl)furan-2-carboxylate (CAS 371208-02-5)
- D-[γ-Glu](Side Chain)-Semaglutide (CAS CATO-C4X-2226254)
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