5-(4-Fluorophenyl)-2-hydroxybenzaldehyde CAS 847754-82-9
| CAS No. | 847754-82-9 |
| Molecular Formula | C13H9FO2 |
| Molecular Weight | 216.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-(4-Fluorophenyl)-2-hydroxybenzaldehyde (CAS 847754-82-9), molecular formula C13H9FO2 and molecular weight 216.21 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(4-Fluorophenyl)-2-hydroxybenzaldehyde (C13H9FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C13H9FO2 |
| Molecular Weight | 216.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Fluorophenyl Standards
- (E)-3-(2-fluorophenyl)-1-(furan-3-yl)prop-2-en-1-one (CAS 1164555-67-2)
- (E)-1-(4-Fluorophenyl)-3-(furan-2-yl)prop-2-en-1-one (CAS 1257127-89-1)
- 5-(2-Fluorophenyl)nicotinamide (CAS 1346691-43-7)
- 5-(4-Fluorophenyl)nicotinamide (CAS 1356110-50-3)
- 5-(3-Fluorophenyl)nicotinamide (CAS 1356110-53-6)
- (E)-3-(4-Fluorophenyl)-1-(furan-2-yl)prop-2-en-1-one (CAS 135950-64-0)
- (2E)-1-(4-Fluorophenyl)-3-(furan-2-yl)prop-2-en-1-one (CAS 1565-90-8)
- (4-Fluorophenyl)(3-hydroxyphenyl)methanone (CAS 62810-47-3)
Recommended Standards
- 5-(((Carboxymethyl)thio)methyl)furan-2-carboxylic acid (CAS 90111-52-7)
- 5-[(methoxycarbonyl)amino]-3-methyl-1,2-thiazole-4-carboxylic acid (CAS 871544-54-6)
- 4-Phenoxy-3-fluorobenzaldehyde, 97% (CAS 887576-87-6)
- 5-AMino-1-(3-fluorophenyl)-3-methyl-1h-pyrazole-4-carbonitrile (CAS 51516-83-7)
- (2E)-1-[4-(1H-1,3-Benzodiazol-1-yl)phenyl]-3-[(4-methylphenyl)amino]prop-2-en-1-one (CAS 691887-93-1)
- ethyl 5-amino-1-(4,6-dimethylpyrimidin-2-yl)-1H-pyrazole-4-carboxylate (CAS 91644-39-2)
- CAS 2389048-49-9 (CAS 2389048-49-9)
- Butyl 6,8-difluoro-4-(pyrrolidin-1-yl)quinoline-2-carboxylate (CAS 1951439-91-0)
- 5-Pentylpyrimidine-2-carboxylic acid (CAS 72790-10-4)
- N-Nitroso Desloratadine (CAS 1246819-22-6)
- 3-Hydroxy-2-(pyridin-3-yl)imidazolidin-4-one (CAS 27230-66-6)
- 3-Bromo-5-isobutyl-1H-1,2,4-triazole (CAS 141831-73-4)
- 1-(2,4-Dihydroxyphenyl)-2-((2-hydroxyethyl)thio)ethan-1-one (CAS 1152899-02-9)
- Tau Peptide (74-102) (Exon 3/Insert 2 Domain) trifluoroacetate salt (CAS 1322695-34-0)
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