4-amino-3-(trifluoromethoxy)phenol CAS 847872-12-2
| CAS No. | 847872-12-2 |
| Molecular Formula | C7H6F3NO2 |
| Molecular Weight | 193.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-amino-3-(trifluoromethoxy)phenol (CAS 847872-12-2), a certified reference material (molecular formula C7H6F3NO2, MW 193.12 g/mol) for analytical method development and quality control.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 4-amino-3-(trifluoromethoxy)phenol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 193.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-amino-3-(trifluoromethoxy)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6F3NO2 |
| Molecular Weight | 193.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related amino Standards
- 2-Amino-5-(trifluoromethoxy)phenol (CAS 117338-14-4)
- 2-Amino-6-(Trifluoromethoxy)phenol (CAS 1261524-09-7)
- 3-Amino-4-(trifluoromethoxy)phenol (CAS 1261581-61-6)
- 3-Amino-5-(trifluoromethoxy)phenol (CAS 1261650-51-4)
- 2-Amino-4-(trifluoromethoxy)phenol (CAS 461699-34-3)
- 4-Amino-2-(trifluoromethoxy)phenol (CAS 847872-07-5)
- (4-Amino-2-(trifluoromethyl)pyrimidin-5-yl)methanol (CAS 1514-01-8)
- 2-Amino-3-methyl-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 216016-31-8)
Recommended Standards
- 5-(hydroxymethyl)-2-(trifluoromethyl)pyridin-1-ium-1-olate (CAS 915369-89-0)
- 4-(2,2,2-Trifluoro-1-hydroxyethyl)pyridin-2(1H)-one (CAS 251352-67-7)
- 5-Hydroxyamino-2-trifluoromethylphenol (CAS 2088942-42-9)
- 3-Bromooctane (CAS 999-64-4)
- (1S)-2-azido-1-(4-methylphenyl)ethan-1-ol (CAS 297765-46-9)
- 1-(4-Bromobenzyl)azetidine-3-carboxylic acid (CAS 1340287-23-1)
- 4,4''-Oxydi-1,1'-biphenyl (CAS 58841-70-6)
- Ethyl 4-fluoropyrimidine-2-carboxylate (CAS 1803818-63-4)
- Tert-butyl (r)-3-(3,3-dimethylureido)piperidine-1-carboxylate (CAS 1286207-28-0)
- Fenpiverinium Bromide (CAS 125-60-0)
- (3,4-Difluorophenyl)(3,4-dimethylphenyl)methanone (CAS 518993-32-3)
- Fumonisin B1 (CAS 116355-83-0)
- Ethyl 5-Cyclopropylisoxazole-3-carboxylate (CAS 21080-81-9)
- D-allo-Thr5-Semaglutide (CAS CATO-C4X-2226243)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com