7-Bromo-4-methoxyquinolin-2(1H)-one CAS 847900-68-9
| CAS No. | 847900-68-9 |
| Molecular Formula | C10H8BrNO2 |
| Molecular Weight | 254.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
7-Bromo-4-methoxyquinolin-2(1H)-one (CAS 847900-68-9), molecular formula C10H8BrNO2 and molecular weight 254.08 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7-Bromo-4-methoxyquinolin-2(1H)-one (C10H8BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8BrNO2 |
| Molecular Weight | 254.08 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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Recommended Standards
- 7-Bromo-4-hydroxy-3-methylquinolin-2(1H)-one (CAS 2322887-49-8)
- 7-Bromo-6-methoxy-1(2H)-isoquinolinone (CAS 924271-34-1)
- 7-Bromo-1-methyl-1H-indole-2-carboxylic acid (CAS 908135-49-9)
- 7-Bromo-6-methoxyquinolin-4-ol (CAS 99073-86-6)
- YM 758 Phosphate (CAS 312752-86-6)
- 2-Iodo-1h-pyrrolo[2,3-c]pyridine (CAS 1227270-26-9)
- 3-Bromo-N-(furan-3-ylmethyl)-N-(2-(thiophen-2-yl)ethyl)benzamide (CAS 1421442-59-2)
- 3-((2,3-Dichlorophenyl)amino)-3-oxopropanoic acid (CAS 95262-11-6)
- 6-Bromo-2-chloro-5-methyl-8-(1-methylcyclopentyl)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 1956322-12-5)
- 5-Bromo-4-chloro-3-indolyl α-D-N-acetylneuraminic acid sodium salt, 98% (CAS 160369-85-7)
- 2-(2-(Hydroxymethyl)phenyl)acetic acid (CAS 63777-42-4)
- Rabeprazole impurity 50 (CAS CATO-C4X-112150)
- METHYL 2-FORMYLTHIOPHENE-3-CARBOXYLATE (CAS 24647-82-3)
- (Des-Gly2)-Exenatide trifluoroacetate salt (CAS 1678416-78-8)
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