1,1,1-Trifluoro-N-(1-isobutyl-1,2,3,4-tetrahydro-quinolin-7-yl)methanesulfonamide CAS 848080-35-3

Purity 97%+In StockPharmaceutical Standards
CAS No.848080-35-3
Molecular FormulaC14H19F3N2O2S
Molecular Weight336.37 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,1,1-Trifluoro-N-(1-isobutyl-1,2,3,4-tetrahydro-quinolin-7-yl)methanesulfonamide CAS 848080-35-3 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

1,1,1-Trifluoro-N-(1-isobutyl-1,2,3,4-tetrahydro-quinolin-7-yl)methanesulfonamide (CAS 848080-35-3) is a high-purity analytical reference standard with the molecular formula C14H19F3N2O2S and a molecular weight of 336.37 g/mol.

The molecular framework of 1,1,1-Trifluoro-N-(1-isobutyl-1,2,3,4-tetrahydro-quinolin-7-yl)methanesulfonamide (C14H19F3N2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

As a certified reference material (CRM), 1,1,1-Trifluoro-N-(1-isobutyl-1,2,3,4-tetrahydro-quinolin-7-yl)methanesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC14H19F3N2O2S
Molecular Weight336.37 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1987
Halogen ContentF-containing
Nitrogen Atoms2
Sulfur Atoms1

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