6-Chloro-N-(pyridin-2-yl)pyrazine-2-carboxamide CAS 848187-27-9
| CAS No. | 848187-27-9 |
| Molecular Formula | C10H7ClN4O |
| Molecular Weight | 234.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-N-(pyridin-2-yl)pyrazine-2-carboxamide (C10H7ClN4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
6-Chloro-N-(pyridin-2-yl)pyrazine-2-carboxamide (CAS 848187-27-9) is a high-purity analytical reference standard with the molecular formula C10H7ClN4O and a molecular weight of 234.64 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-N-(pyridin-2-yl)pyrazine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN4O |
| Molecular Weight | 234.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-3-nitro-2-phenylpyridine (CAS 1049706-69-5)
- 6-Chloro-3-(3-methylfuran-2-yl)-[1,2,4]triazolo[4,3-b]pyridazine (CAS 1094260-40-8)
- 5-Chloro-2-phenylpyrimidine-4-carboxylic acid (CAS 1094346-84-5)
- 2-Chloro-5-nitro-3-phenylpyridine (CAS 1119088-46-8)
- 2-Chloro-6-phenylpyrimidine-4-carboxylic acid (CAS 1181985-99-8)
- 2-Chloro-6-(pyridin-2-yl)pyridine-3-carboxylic acid (CAS 1192424-12-6)
- 2-Chloro-6-(pyridin-4-yl)pyridine-4-carboxylic acid (CAS 1214346-00-5)
- 2-Chloro-6-(pyridin-3-yl)pyridine-4-carboxylic acid (CAS 1214368-46-3)
Recommended Standards
- 6-Chloro-2-phenylpyrimidine-4-carboxylic acid (CAS 913952-59-7)
- 9-Chloro-2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5(6H)-one (CAS 882517-76-2)
- 6-Chloro-[2,4'-bipyridine]-5-carboxylic acid (CAS 65049-27-6)
- Methyl 2-(2-chloroacetyl)-6-oxohexahydropyridazine-4-carboxylate (CAS 251307-08-1)
- 3-Chloro-n-(piperidin-4-yl)pyridin-4-amine (CAS 1517110-55-2)
- (6-Oxopiperidin-3-yl)methyl 4-methylbenzenesulfonate (CAS 2879334-87-7)
- Methyl 2-bromo-2-(pyridin-2-yl)acetate (CAS 52458-81-8)
- 4-Isopropoxy-2-methyl-6-(piperazin-1-yl)pyrimidine (CAS 1706428-19-4)
- 2-(2-Bromo-5-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1256781-59-5)
- CAS 2315262-47-4 (CAS 2315262-47-4)
- Ethyl 1-methyl-1,6-dihydropyrrolo[2,3-c]pyrazole-5-carboxylate (CAS 1379175-53-7)
- 4-Ethyl-5-(1-(o-tolyloxy)ethyl)-4H-1,2,4-triazole-3-thiol (CAS 588673-87-4)
- Sitagliptin Impurity 78-d4 (CAS 2892260-32-9 (unlabelled))
- Palmitoyl Hexapeptide-12 (CAS 171263-26-6)
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