5-Bromo-3-chloro-2-methoxypyridine, 97% CAS 848366-28-9
| CAS No. | 848366-28-9 |
| Molecular Formula | C6H5BrClNO |
| Molecular Weight | 222.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Bromo-3-chloro-2-methoxypyridine, 97% meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Bromo-3-chloro-2-methoxypyridine, 97% (CAS 848366-28-9) is a high-purity analytical reference standard with the molecular formula C6H5BrClNO and a molecular weight of 222.47 g/mol.
The molecular framework of 5-Bromo-3-chloro-2-methoxypyridine, 97% (C6H5BrClNO) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H5BrClNO |
| Molecular Weight | 222.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 4-Bromo-2-chloro-5-methoxypyridine (CAS 1020253-15-9)
- 3-Bromo-5-chloro-2-methoxypyridine (CAS 102830-75-1)
- 3-Bromo-2-chloro-5-methoxypyridine (CAS 1033202-44-6)
- 5-Bromo-4-chloro-2-methylpyridine 1-oxide (CAS 103971-43-3)
- (5-Bromo-4-chloropyridin-2-yl)methanol (CAS 103971-44-4)
- (3-Bromo-5-chloropyridin-4-yl)methanol (CAS 1064677-18-4)
- 5-Bromo-4-chloropyridine-2,3-diamine (CAS 1131604-99-3)
- 5-Bromo-6-chloropyridine-2,3-diamine (CAS 1195519-49-3)
Recommended Standards
- 5-Bromo-3-chloro-1-methylpyridin-2(1H)-one (CAS 889865-52-5)
- 5-Bromo-3-chloro-N-methylpyrazin-2-amine (CAS 446286-77-7)
- 5-Bromo-2-chloro-N-methyl-4-pyrimidinamine (CAS 205672-24-8)
- 5-Bromo-4-chloro-2-methoxypyridine (CAS 851607-27-7)
- 1-(2,4-Dichlorobenzyl)-2-methyl-1H-benzo[d]imidazole-6-carboxylic acid (CAS 193010-16-1)
- (Furan-2-ylmethyl)hydrazine (CAS 6885-12-7)
- Ethyl 4-(2,4,6-trimethylphenyl)-4-oxobutanoate (CAS 31419-99-5)
- Isopentyltriphenylphosphonium iodide (CAS 52710-37-9)
- 4-Methanesulfonyl-morpholine-3-carboxylic acid (CAS 1316217-87-4)
- 2,2,2-Trifluoro-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 2946-73-8)
- Methyl 2-chloro-4-(4-chlorophenyl)benzoate (CAS 1820716-21-9)
- 2-(4-Chlorophenyl)indolizine-3-carbaldehyde (CAS 558424-57-0)
- 1-(2-Aminoethyl)piperidin-2-one (CAS 27578-61-6)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com