5-Aminothiazolo[4,5-d]pyrimidin-2(3H)-one CAS 848691-22-5
| CAS No. | 848691-22-5 |
| Molecular Formula | C5H4N4OS |
| Molecular Weight | 168.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Aminothiazolo[4,5-d]pyrimidin-2(3H)-one is closely related to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Aminothiazolo[4,5-d]pyrimidin-2(3H)-one (CAS 848691-22-5), a certified reference material (molecular formula C5H4N4OS, MW 168.18 g/mol) for analytical method development and quality control.
The molecular framework of 5-Aminothiazolo[4,5-d]pyrimidin-2(3H)-one (C5H4N4OS) is characterized by an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Aminothiazolo[4,5-d]pyrimidin-2(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H4N4OS |
| Molecular Weight | 168.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Aminothiazolo Standards
- 7-Aminothiazolo[4,5-d]pyrimidin-2(3H)-one (CAS 122970-56-3)
- 2-Aminothiazolo[5,4-b]pyridin-5-ol (CAS 31784-73-3)
- 2-Aminothiazolo[4,5-b]pyridin-5(4H)-one (CAS 13575-44-5)
- 2-Aminothiazolo[4,5-d]pyrimidine-5,7(4H,6H)-dione (CAS 30161-91-2)
- 5-Aminothiazolo[4,5-d]pyrimidine-2(3H)-thione (CAS 892498-86-1)
- Methyl 2-aminothiazolo[5,4-b]pyridine-7-carboxylate (CAS 1206248-00-1)
- Methyl 2-aminothiazolo[4,5-b]pyridine-6-carboxylate (CAS 1206248-27-2)
- Methyl 6-aminothiazolo[5,4-c]pyridine-2-carboxylate (CAS 1206250-15-8)
Recommended Standards
- 5-Amino-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one (CAS 59716-88-0)
- 6-Thioxo-7,9-dihydro-1H-purin-8(6H)-one (CAS 20917-46-8)
- 5-(1,2-Oxazol-3-yl)-1,3,4-thiadiazol-2-amine (CAS 70057-77-1)
- 7-Amino-1H-[1,2,3]triazolo[4,5-d]pyrimidine-5-thiol (CAS 87866-18-0)
- 1-(2-Amino-3-methylbutyl)pyrrolidine-2,5-dione (CAS 1339379-36-0)
- 3-((2-(3,4-Dihydroquinolin-1(2H)-yl)-2-oxoethyl)thio)-6-methyl-1,2,4-triazin-5(4H)-one (CAS 296773-82-5)
- 2-(1H-indol-7-yl)acetic acid (CAS 39689-63-9)
- 2-Bromo-5-(cyclopropylmethoxy)pyridine (CAS 1177269-06-5)
- 4-Ethoxybutanoic Acid (CAS 10374-37-5)
- 2-(Chloromethyl)-6-methoxyquinazoline (CAS 1936095-76-9)
- Tert-butyl 3,5-dimethylmorpholine-4-carboxylate (CAS 942309-59-3)
- Tert-butyl 8-formyl-5-azaspiro[2.5]Octane-5-carboxylate (CAS 2411639-63-7)
- 5-(Difluoromethyl)-3-nitropyrazolo[1,5-a]pyrimidine (CAS 1823818-09-2)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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