Ethyl 6-Chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate CAS 849068-50-4
| CAS No. | 849068-50-4 |
| Molecular Formula | C10H9ClN2O2 |
| Molecular Weight | 224.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 6-Chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate.
Ethyl 6-Chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate (CAS 849068-50-4), molecular formula C10H9ClN2O2 and molecular weight 224.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 6-Chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate (C10H9ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 6-Chloro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN2O2 |
| Molecular Weight | 224.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- Ethyl 6-chloro-1H-indazole-3-carboxylate (CAS 885279-23-2)
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- Ethyl 5-chloroimidazo[1,5-a]pyridine-1-carboxylate (CAS 885271-54-5)
- Ethyl 6-chloro-2H-indazole-5-carboxylate (CAS 2115903-05-2)
- 4,8-Dihydroxycoumarin (CAS 106754-20-5)
- N-benzyl-2-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-2-oxoacetamide (CAS 1300030-83-4)
- 2,6-Dichloro-3-(difluoromethoxy)phenacyl chloride (CAS 1807037-80-4)
- (17β)-17-Hydroxy-17-methyl-estra-5(10),9(11)-dien-3-one Cyclic 1,2-Ethanediyl Acetal (CAS 54690-62-9)
- Serotonin Impurity 12 (CAS CATO-C4X-253412)
- 5-Bromo-n-((3r)-6-methylquinuclidin-3-yl)thiazole-2-carboxamide (CAS 524697-62-9)
- (1S,5R,6S)-5-Hydroxy-3-((S)-1-hydroxy-3-methylbut-2-en-1-yl)-7-oxabicyclo[4.1.0]hept-3-en-2-one (CAS 31298-54-1)
- Phytomenadione/Vitamin K1 Impurity 117 (CAS CATO-C4X-2207117)
- 2-Bromo-7-(methoxymethoxy)naphthalene (CAS 2158298-25-8)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
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