2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine CAS 849934-84-5
| CAS No. | 849934-84-5 |
| Molecular Formula | C14H19BF3NO3 |
| Molecular Weight | 317.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 317.11 g/mol gives 2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine (CAS 849934-84-5), molecular formula C14H19BF3NO3 and molecular weight 317.11 g/mol, is a CATO reference standard with documented purity and traceability.
2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridine (C14H19BF3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H19BF3NO3 |
| Molecular Weight | 317.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 4-Bromo-5-(difluoromethyl)-3-methoxypyridine-2-sulfonamide (CAS 1806908-55-3)
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- 6-Bromo-5-(difluoromethyl)-2-methoxypyridine-3-sulfonamide (CAS 1806906-02-4)
- 3-((4-Iodo-2-methylphenyl)amino)dihydrofuran-2(3h)-one (CAS 1008571-10-5)
- 2,5-Difluoro-N-(4-fluorobenzyl)aniline (CAS 1019585-04-6)
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- Sildenafil Impurity 45 (CAS 62871-12-9)
- N-Benzyl-4-fluorobenzo[d]thiazol-2-amine (CAS 862975-05-1)
- Gabexate (CAS 39492-01-8)
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