(3S,4S)-1-benzyl-4-(hydroxymethyl)pyrrolidin-3-ol CAS 849935-80-4
| CAS No. | 849935-80-4 |
| Molecular Formula | C12H17NO2 |
| Molecular Weight | 207.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3S,4S)-1-benzyl-4-(hydroxymethyl)pyrrolidin-3-ol (CAS 849935-80-4) is a high-purity analytical reference standard with the molecular formula C12H17NO2 and a molecular weight of 207.27 g/mol.
(3S,4S)-1-benzyl-4-(hydroxymethyl)pyrrolidin-3-ol (C12H17NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3S,4S)-1-benzyl-4-(hydroxymethyl)pyrrolidin-3-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H17NO2 |
| Molecular Weight | 207.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 1 |
Recommended Standards
- (3R,5R)-5-Ethoxy-3-methyl-2-phenylisoxazolidine (CAS 220004-05-7)
- (3S,5R)-1-Benzyl-5-hydroxymethyl-pyrrolidin-3-ol (CAS 635299-90-0)
- (3R,4S)-4-(((S)-1-phenylethyl)amino)tetrahydrofuran-3-ol (CAS 335080-43-8)
- (3S,5S)-1-benzyl-5-(hydroxymethyl)pyrrolidin-3-ol (CAS 635299-92-2)
- 2-(2-Fluorophenyl)-1-(3-iodophenyl)ethan-1-one (CAS 898784-75-3)
- 1-Ethyl-2-(iodomethyl)-1h-imidazole (CAS 1343182-17-1)
- (R)-2-Amino-4-(4-(tert-butyl)phenyl)butanoic acid (CAS 1260605-82-0)
- 3-bromo-5-methyl-1H-pyrazolo[4,3-d]pyrimidine (CAS 1545353-97-6)
- Resmetirom Impurity 41 (CAS 2403724-55-8)
- 2,3-Difluoro-4'-propyl-1,1'-biphenyl (CAS 126163-02-8)
- Methyl 2-(cyclopropylamino)-2-(4-hydroxyphenyl)acetate (CAS 1218087-43-4)
- Sodium (E)-3-(8-(3-methoxystyryl)-7-methyl-2,6-dioxo-1-(prop-2-yn-1-yl)-1,2,6,7-tetrahydro-3H-purin-3-yl)propyl phosphate (CAS 261717-23-1)
- 34403-52-6 4-(aminomethyl)-N,N-dimethylaniline dihydrochloride 4-Dimethylaminobenzylamine dihydrochloride (CAS 34403-52-6)
- D-Ala21-Tirzepatide (CAS CATO-CPTD788913)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com