(4-Chlorophenyl)(2-hydroxy-4-methoxyphenyl)methanone CAS 85-28-9
| CAS No. | 85-28-9 |
| Molecular Formula | C14H11ClO3 |
| Molecular Weight | 262.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system, (4-Chlorophenyl)(2-hydroxy-4-methoxyphenyl)methanone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 262.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
(4-Chlorophenyl)(2-hydroxy-4-methoxyphenyl)methanone (CAS 85-28-9) is a high-purity analytical reference standard with the molecular formula C14H11ClO3 and a molecular weight of 262.69 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (4-Chlorophenyl)(2-hydroxy-4-methoxyphenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11ClO3 |
| Molecular Weight | 262.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- 3-[(4-chlorophenyl)methoxy]benzoic acid (CAS 112944-97-5)
- 1-(4-Chlorophenyl)-N-(4h-1,2,4-triazol-3-yl)cyclopropane-1-carboxamide (CAS 1210974-78-9)
- 2-(5-(4-Chlorophenyl)furan-2-yl)cyclopropanecarboxylic acid (CAS 1315348-98-1)
- 1-(4-Chlorophenyl)-3-(prop-2-yn-1-ylamino)pyrrolidine-2,5-dione (CAS 1415719-07-1)
- 2-(4-Chlorophenyl)-7,8-dihydro-3H-pyrano[4,3-d]pyrimidin-4(5H)-one (CAS 1450790-52-9)
- 1-(4-Chlorophenyl)-3-(1-methyl-1H-pyrazol-4-yl)propane-1,3-dione (CAS 1503529-33-6)
- 2-(4-Chlorophenyl)-1-(2,4-dihydroxyphenyl)ethan-1-one (CAS 15485-64-0)
- Methyl 4-(4-chlorophenyl)-2-hydroxybenzoate (CAS 1820716-98-0)
Recommended Standards
- (2e)-3-(5-Chloro-3-methyl-1-phenyl-1h-pyrazol-4-yl)prop-2-enoic acid (CAS 27268-07-1)
- (E)-3-(5-(3-chloro-4-methylphenyl)furan-2-yl)acrylic acid (CAS 843638-64-2)
- N-(4-Amino-2-hydroxyphenyl)-4-chlorobenzamide (CAS 196394-23-7)
- 1-(3-Chloro-4-methylphenyl)-3-(pyrimidin-2-yl)urea (CAS 64699-76-9)
- tert-Butyl 6-bromo-3-azabicyclo[3.1.0]hexane-3-carboxylate (CAS 2166747-26-6)
- n-Methyl-2-(morpholin-2-yl)acetamide (CAS 1502510-04-4)
- Tert-Butylhydrazine Hydrochloride (CAS 7400-27-3)
- (2-bromo-4,5-diethoxybenzyl)hydrazine hydrochloride (CAS 926199-79-3)
- Ethyl 2-(aminomethyl)-3,3-difluoropropanoate hydrochloride (CAS 1393532-78-9)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
- tert-Butyl (5-chlorobenzo[d]oxazol-7-yl)carbamate (CAS 1356111-25-5)
- 2,2-Difluoro-1-(3,3,3-trifluoro-3,4-dihydro-3λ5-pyridin-4-yl)ethan-1-ol (CAS 886496-24-8)
- N-(Furan-2-ylmethylene)-3-methylaniline (CAS 134127-17-6)
- Compstatin control peptide (CAS 301544-78-5)
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